The life cycle of coagulation factor VIII in view of its structure and function.
about
Potential role of a new PEGylated recombinant factor VIII for hemophilia A.Progress and challenges in the development of a cell-based therapy for hemophilia AThe tertiary structure and domain organization of coagulation factor VIIIDomain organization of membrane-bound factor VIII.Structure of the factor VIII C2 domain in a ternary complex with 2 inhibitor antibodies reveals classical and nonclassical epitopesClinical and laboratory approaches to hemophilia aFactoring in Factor VIII With Acute Ischemic StrokeChemical chaperones improve protein secretion and rescue mutant factor VIII in mice with hemophilia ACompound heterozygous hemophilia A in a female patient and the identification of a novel missense mutation, p.Met1093IleA new recombinant factor VIII: from genetics to clinical use.Dimeric Organization of Blood Coagulation Factor VIII bound to Lipid Nanotubes.Endogenous factor VIII synthesis from the intron 22-inverted F8 locus may modulate the immunogenicity of replacement therapy for hemophilia AAnalysis and accurate quantification of CpG methylation by MALDI mass spectrometry.Models for prediction of factor VIII half-life in severe haemophiliacs: distinct approaches for blood group O and non-O patients.Comparative response of platelet fV and plasma fV to activated protein C and relevance to a model of acute traumatic coagulopathy.Haemophilia A and haemophilia B: molecular insightsRegulation of the protein C anticoagulant and antiinflammatory pathways.Storage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cellsSoy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted factor VIII in hemophilia A mice.The molecular basis of factor V and VIII procofactor activationBlood coagulation factors V and VIII: Molecular Mechanisms of Procofactor Activation.Proteomic characterization of plasma-derived clotting factor VIII-von Willebrand factor concentrates.Laser capture microdissected mucosa versus whole tissue specimens for assessment of radiation-induced dynamic molecular and pathway changes in the small intestineDesigned ankyrin repeat proteins: a new approach to mimic complex antigens for diagnostic purposes?The 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfacesEffect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.Human coagulation factor VIII domain-specific recombinant polypeptide expressionFactor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings.A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytesStructure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody.Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13.Characterization and solution structure of the factor VIII C2 domain in a ternary complex with classical and non-classical inhibitor antibodies.Interaction of dicaproyl phosphatidylserine with recombinant factor VIII and its impact on immunogenicityPassive transfer of polyethylene glycol to liposomal-recombinant human FVIII enhances its efficacy in a murine model for hemophilia A.Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII)Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway.Storage and regulated secretion of factor VIII in blood outgrowth endothelial cellsMeasurement of hemostatic factors in EDTA plasmaA population pharmacokinetic model for perioperative dosing of factor VIII in hemophilia A patientsCircumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.
P2860
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P2860
The life cycle of coagulation factor VIII in view of its structure and function.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The life cycle of coagulation factor VIII in view of its structure and function.
@ast
The life cycle of coagulation factor VIII in view of its structure and function.
@en
The life cycle of coagulation factor VIII in view of its structure and function.
@nl
type
label
The life cycle of coagulation factor VIII in view of its structure and function.
@ast
The life cycle of coagulation factor VIII in view of its structure and function.
@en
The life cycle of coagulation factor VIII in view of its structure and function.
@nl
prefLabel
The life cycle of coagulation factor VIII in view of its structure and function.
@ast
The life cycle of coagulation factor VIII in view of its structure and function.
@en
The life cycle of coagulation factor VIII in view of its structure and function.
@nl
P2093
P1433
P1476
The life cycle of coagulation factor VIII in view of its structure and function.
@en
P2093
Lenting PJ
van Mourik JA
P304
P407
P577
1998-12-01T00:00:00Z