about
Inhibition of DNA-dependent protein kinase catalytic subunit by small molecule inhibitor NU7026 sensitizes human leukemic K562 cells to benzene metabolite-induced apoptosisRegulation and localization of the Bloom syndrome protein in response to DNA damageThe role of DNA polymerase activity in human non-homologous end joiningTyrosine phosphorylation enhances RAD52-mediated annealing by modulating its DNA binding.Differential effects of Rad52p overexpression on gene targeting and extrachromosomal homologous recombination in a human cell lineVisualization of recombination intermediates produced by RAD52-mediated single-strand annealingInvolvement of human polynucleotide kinase in double-strand break repair by non-homologous end joiningThe Rad51 paralog Rad51B promotes homologous recombinational repairDisruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin CKu recruits the XRCC4-ligase IV complex to DNA endsHomologous-pairing activity of the human DNA-repair proteins Xrcc3.Rad51CDeficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningThe architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNAEndogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancerGenetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombinationRAD51 localization and activation following DNA damageMegabase chromatin domains involved in DNA double-strand breaks in vivoHomologous Recombination and Its Role in CarcinogenesisGene conversion and deletion frequencies during double-strand break repair in human cells are controlled by the distance between direct repeatsUVA-visible photo-excitation of guanine radical cations produces sugar radicals in DNA and model structuresAdvances in mechanisms of genetic instability related to hereditary neurological diseases.Gene targeting, genome editing: from Dolly to editorsTowards a new era in medicine: therapeutic genome editingHsp90: A New Player in DNA Repair?RecQ helicases in DNA double strand break repair and telomere maintenance.Functional cross-talk among Rad51, Rad54, and replication protein A in heteroduplex DNA joint formation.Exposure of single-stranded telomeric DNA causes G2/M cell cycle arrest in Saccharomyces cerevisiae.Arabidopsis DNA ligase IV is induced by gamma-irradiation and interacts with an Arabidopsis homologue of the double strand break repair protein XRCC4.LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiaeFunctional interaction between Ku and the werner syndrome protein in DNA end processingDNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining systemCell-penetrating peptide-mediated delivery of TALEN proteins via bioconjugation for genome engineeringThe mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with AtmTargeting the DNA double strand break repair machinery in prostate cancerChromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogsA new recombinational DNA repair gene from Schizosaccharomyces pombe with homology to Escherichia coli RecA.Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.Identification of proteins in the hamster DNA end-binding complex.Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks.Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Molecular mechanisms of DNA double strand break repair.
@ast
Molecular mechanisms of DNA double strand break repair.
@en
Molecular mechanisms of DNA double strand break repair.
@nl
type
label
Molecular mechanisms of DNA double strand break repair.
@ast
Molecular mechanisms of DNA double strand break repair.
@en
Molecular mechanisms of DNA double strand break repair.
@nl
prefLabel
Molecular mechanisms of DNA double strand break repair.
@ast
Molecular mechanisms of DNA double strand break repair.
@en
Molecular mechanisms of DNA double strand break repair.
@nl
P2093
P1476
Molecular mechanisms of DNA double strand break repair.
@en
P2093
Hoeijmakers JH
van Gent DC
P304
P356
10.1016/S0962-8924(98)01383-X
P577
1998-12-01T00:00:00Z