Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis. - Wikidata - wikimedia - TriplyDB

Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis.

Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis.

http://www.wikidata.org/entity/Q34485836

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Sphingolipids in High Fat Diet and Obesity-Related Diseases Regulation of Nlrp3 inflammasome by dietary metabolites High-Mobility Group Box 1 Disrupts Metabolic Function with Cigarette Smoke Exposure in a Ceramide-Dependent Manner.Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans.BMI-related progression of atypical PKC-dependent aberrations in insulin signaling through IRS-1, Akt, FoxO1 and PGC-1α in livers of obese and type 2 diabetic humans An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease.An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice.Temporal changes in sphingolipids and systemic insulin sensitivity during the transition from gestation to lactation Macrophage-specific de Novo Synthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity.Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.Adiponectin, the past two decades.Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk.Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis Chronic Glucocorticoid-Rich Milieu and Liver Dysfunction Circulating ceramides are inversely associated with cardiorespiratory fitness in participants aged 54-96 years from the Baltimore Longitudinal Study of Aging Lipid profiling of the therapeutic effects of berberine in patients with nonalcoholic fatty liver disease.Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis.Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance.Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis.Targeting adipose tissue in the treatment of obesity-associated diabetes.Targeting ceramide metabolism in obesity.Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis.Adiponectin and its Hydrolase-Activated Receptors.Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism.Adiponectin serenades ceramidase to improve metabolism.Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation.The Multifaceted Roles of Adipose Tissue-Therapeutic Targets for Diabetes and Beyond: The 2015 Banting Lecture.Obesity-induced changes in lipid mediators persist after weight loss.Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity.Development and validation of a high-throughput LC-MS/MS assay for routine measurement of molecular ceramides.A Lipidomics Approach to Assess the Association Between Plasma Sphingolipids and Verbal Memory Performance in Coronary Artery Disease Patients Undertaking Cardiac Rehabilitation: A C18:0 Signature for Cognitive Response to Exercise.Endogenous acid ceramidase protects epithelial cells from Porphyromonas gingivalis-induced inflammation in vitro.Mechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in mice.Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.Sphingolipids and their metabolism in physiology and disease.Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis.Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.Metabolic profiling of follistatin overexpression: a novel therapeutic strategy for metabolic diseases.Absence of ANGPTL4 in adipose tissue improves glucose tolerance and attenuates atherogenesis.PPARγ and its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization.

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Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis.

http://www.wikidata.org/entity/Q34485836

description

2015 nî lūn-bûn

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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2015 թվականի հուլիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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J.CMET.2015.06.007

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Cell Metabolism

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Targeted Induction of Ceramide ...... and Reduced Hepatic Steatosis.

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Angelika J Sifuentes

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Christine M Kusminski

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Jeffrey G McDonald

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Jonathan Y Xia

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Kai Sun

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Mackenzie J Pearson

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Philipp E Scherer

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William L Holland

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P2860

Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

The adipokine/ceramide axis: key aspects of insulin sensitization

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

Permissive action of protein kinase C-zeta in insulin-induced CD36- and GLUT4 translocation in cardiac myocytes

Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

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266-278

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10.1016/J.CMET.2015.06.007

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