CK2-mediated hyperphosphorylation of topoisomerase I targets serine 506, enhances topoisomerase I-DNA binding, and increases cellular camptothecin sensitivity.
about
Decreased camptothecin sensitivity of the stem-cell-like fraction of Caco2 cells correlates with an altered phosphorylation pattern of topoisomerase IThe p14ARF alternate reading frame protein enhances DNA binding of topoisomerase I by interacting with the serine 506-phosphorylated core domain.Proteomic characterization of the nucleolar linker histone H1 interaction network.Topoisomerase-I PS506 as a Dual Function Cancer Biomarker.Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines.Topoisomerase I as a biomarker: detection of activity at the single molecule level.Quantum dot-based nanosensors for diagnosis via enzyme activity measurement.Protein kinase CK2 in breast cancer: the CK2β regulatory subunit takes center stage in epithelial plasticity.RNA-seq reveals determinants for irinotecan sensitivity/resistance in colorectal cancer cell lines.Characterization and antitumor activity of camptothecin from endophytic fungus Fusarium solani isolated from Camptotheca acuminate.
P2860
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P2860
CK2-mediated hyperphosphorylation of topoisomerase I targets serine 506, enhances topoisomerase I-DNA binding, and increases cellular camptothecin sensitivity.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@ast
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@en
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@nl
type
label
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@ast
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@en
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@nl
prefLabel
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@ast
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@en
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@nl
P2093
P2860
P1433
P1476
CK2-mediated hyperphosphorylat ...... ular camptothecin sensitivity.
@en
P2093
Keya Bandyopadhyay
Pingchuan Li
Ruth A Gjerset
P2860
P304
P356
10.1371/JOURNAL.PONE.0050427
P407
P577
2012-11-21T00:00:00Z