Activating SRC mutation in a subset of advanced human colon cancers.
about
Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell linesp27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factorBcr interferes with beta-catenin-Tcf1 interactionAdhesion signaling by a novel mitotic substrate of src kinasesThe role of Src in solid tumorsDifferential expression of aquaporin 8 in human colonic epithelial cells and colorectal tumorsInsig2 is associated with colon tumorigenesis and inhibits Bax-mediated apoptosisFaecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancerThe homeobox gene CDX2 in colorectal carcinoma: a genetic analysisSrc kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signalingThe repertoire of protein kinases encoded in the draft version of the human genome: atypical variations and uncommon domain combinationsThe molecular rationale of Src inhibition in colorectal carcinomasAndrogen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinasesAutophagy in malignant transformation and cancer progressionDasatinib sensitizes KRAS mutant colorectal tumors to cetuximabOncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancerA novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRKThe hunting of the SrcRegulation of SRC family kinases in human cancersProteogenomic characterization of human colon and rectal cancerLung Cancer: Are we up to the Challenge?A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRCA novel peptide derived from human apolipoprotein E is an inhibitor of tumor growth and ocular angiogenesisDual-faced SH3BGRL: oncogenic in mice, tumor suppressive in humansC-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases.Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis.The C terminus of c-Src inhibits breast tumor cell growth by a kinase-independent mechanism.The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases.Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival.Novel insight into mutational landscape of head and neck squamous cell carcinomaThe tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.A novel group IIA phospholipase A2 interacts with v-Src oncoprotein from RSV-transformed hamster cells.Identification of the SRC pyrimidine-binding protein (SPy) as hnRNP K: implications in the regulation of SRC1A transcriptionA dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.Cellular processes of v-Src transformation revealed by gene profiling of primary cells--implications for human cancer.C-terminal Src kinase (Csk)-mediated phosphorylation of eukaryotic elongation factor 2 (eEF2) promotes proteolytic cleavage and nuclear translocation of eEF2Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer ProgressionSimultaneous siRNA targeting of Src and downstream signaling molecules inhibit tumor formation and metastasis of a human model breast cancer cell line.
P2860
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P2860
Activating SRC mutation in a subset of advanced human colon cancers.
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Activating SRC mutation in a subset of advanced human colon cancers.
@ast
Activating SRC mutation in a subset of advanced human colon cancers.
@en
Activating SRC mutation in a subset of advanced human colon cancers.
@nl
type
label
Activating SRC mutation in a subset of advanced human colon cancers.
@ast
Activating SRC mutation in a subset of advanced human colon cancers.
@en
Activating SRC mutation in a subset of advanced human colon cancers.
@nl
prefLabel
Activating SRC mutation in a subset of advanced human colon cancers.
@ast
Activating SRC mutation in a subset of advanced human colon cancers.
@en
Activating SRC mutation in a subset of advanced human colon cancers.
@nl
P2093
P356
P1433
P1476
Activating SRC mutation in a subset of advanced human colon cancers.
@en
P2093
Loubeau JM
Yeatman TJ
P2888
P304
P356
10.1038/5971
P407
P577
1999-02-01T00:00:00Z