Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
about
Antamanide, a derivative of Amanita phalloides, is a novel inhibitor of the mitochondrial permeability transition poreGene family encoding the major toxins of lethal Amanita mushroomsOATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamiliesGetting in shape: controlling peptide bioactivity and bioavailability using conformational constraintsActive sulforhodamine 101 uptake into hippocampal astrocytesAcute hepatorenal failure in a patient following consumption of mushrooms: a case reportMushroom poisoning: a retrospective study concerning 11-years of admissions in a Swiss Emergency Department.Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation.TP53 loss creates therapeutic vulnerability in colorectal cancer.Impact of OATP transporters on pharmacokinetics.Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes.Characterization of organic anion transporting polypeptide 1b2-null mice: essential role in hepatic uptake/toxicity of phalloidin and microcystin-LR.The expression and function of organic anion transporting polypeptides in normal tissues and in cancerABC transporter-dependent brain uptake of the 5-HT1B receptor radioligand [ (11)C]AZ10419369: a comparative PET study in mouse, rat, and guinea pigUlcerating Ileocolitis in Severe Amatoxin PoisoningLegalon® SIL: the antidote of choice in patients with acute hepatotoxicity from amatoxin poisoning.In vitro and in vivo drug disposition of cilengitide in animals and human.Treatment heterogeneity in asthma: genetics of response to leukotriene modifiers.Interaction of silymarin flavonolignans with organic anion-transporting polypeptides.Organic anion transporting polypeptides expressed in pancreatic cancer may serve as potential diagnostic markers and therapeutic targets for early stage adenocarcinomasKinetic determinants of hepatic clearance: plasma protein binding and hepatic uptake.Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response.Organic anion-transporting polypeptides.Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.Emerging transporters of clinical importance: an update from the International Transporter Consortium.Getting across the cell membrane: an overview for small molecules, peptides, and proteins.Targeting tumor suppressor genes for cancer therapy.Investigating and analyzing three cohorts of mushroom poisoning caused by Amanita exitialis in Yunnan, China.Near‑infrared fluorescence imaging of prostate cancer using heptamethine carbocyanine dyes.Influence of drug formulation on OATP1B-mediated transport of paclitaxel.Trafficking and other regulatory mechanisms for organic anion transporting polypeptides and organic anion transporters that modulate cellular drug and xenobiotic influx and that are dysregulated in disease.Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma.Montelukast Disposition: No Indication of Transporter-Mediated Uptake in OATP2B1 and OATP1B1 Expressing HEK293 Cells.MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux.Development of a physiologically based pharmacokinetic/pharmacodynamic model to identify mechanisms contributing to entacapone low bioavailability.Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir.Alpha-Amanitin Poisoning, Nephrotoxicity and Oxidative Stress: An Experimental Mouse Model.
P2860
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P2860
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@ast
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@en
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@nl
type
label
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@ast
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@en
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@nl
prefLabel
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@ast
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@en
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@nl
P2093
P356
P1476
Molecular characterization and inhibition of amanitin uptake into human hepatocytes.
@en
P2093
Daniela Keller
Dietrich Keppler
Heinz Faulstich
Katrin Letschert
P304
P356
10.1093/TOXSCI/KFJ141
P577
2006-02-22T00:00:00Z