Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.
about
Systems biology and biomarkers of early effects for occupational exposure limit settingArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research.The utility of DNA microarrays for characterizing genotoxicity.Valproic acid teratogenicity: a toxicogenomics approachIncorporating epigenetic data into the risk assessment process for the toxic metals arsenic, cadmium, chromium, lead, and mercury: strategies and challengesMass spectrometric analyses of organophosphate insecticide oxon protein adductsDioxin in the Elbe river basin: policy and science under the water framework directive 2000-2015 and toward 2021.Integration of metabolomics, lipidomics and clinical data using a machine learning method.The use of in vitro data in risk assessment.Data processing and classification analysis of proteomic changes: a case study of oil pollution in the mussel, Mytilus edulisThe potential of ecotoxicoproteomics in environmental monitoring: biomarker profiling in mussel plasma using ProteinChip array technology.Toxicological protein biomarker analysis--an investigative one-week single dose intravenous infusion toxicity and toxicokinetic study in cynomolgus monkeys using an antibody-cytotoxic conjugate against ovarian cancer.Toxicogenomics: a pivotal piece in the puzzle of toxicological research.Comparison of the specificity and sensitivity of traditional methods for assessment of nephrotoxicity in the rat with metabonomic and proteomic methodologies.Analysis of time course 1H NMR metabolomics data by multivariate curve resolution.A computational toxicogenomics approach identifies a list of highly hepatotoxic compounds from a large microarray database.¹H NMR-based metabolomics approach to assess toxicity of bunker a heavy oil to freshwater carp, Cyprinus carpio.Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology.Pharmacogenetics and pharmacogenomics in drug development and regulatory decision making: report of the first FDA-PWG-PhRMA-DruSafe Workshop.The hunt for new genes and polymorphisms that can control the response to drugs.Cross-species toxicogenomic analyses and phenotypic anchoring in response to groundwater low-level pollutionFunctional toxicogenomics: mechanism-centered toxicology.Toxicogenomics: an opportunity to optimise drug development and safety evaluation.Fold-change threshold screening: a robust algorithm to unmask hidden gene expression patterns in noisy aggregated transcriptome data.Minireview: Epigenetics of obesity and diabetes in humansBiomarkers of exposure in community settings.Biomarkers of cancer risk and therapeutic benefit: new technologies, new opportunities, and some challenges.Unbiased high-throughput characterization of mussel transcriptomic responses to sublethal concentrations of the biotoxin okadaic acid.Toxicogenomics and systems toxicology: aims and prospects.NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition.Ethics and research assessing the relative roles of genes and the environment.Gene expression profile analysis: an emerging approach to investigate mechanisms of genotoxicity.The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements.Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology.The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment.Application of genomics in preclinical drug safety evaluation.Toxicogenomics in drug discovery and drug development: potential applications and future challenges.Gene expression patterns in rainbow trout, Oncorhynchus mykiss, exposed to a suite of model toxicants.Promises of biomarkers in drug development--a reality check.Proteomic applications in ecotoxicology.
P2860
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P2860
Toxicology and genetic toxicology in the new era of "toxicogenomics": impact of "-omics" technologies.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@ast
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@en
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@nl
type
label
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@ast
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@en
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@nl
prefLabel
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@ast
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@en
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@nl
P1433
P1476
Toxicology and genetic toxicol ...... pact of "-omics" technologies.
@en
P2093
James T MacGregor
Marilyn J Aardema
P356
10.1016/S0027-5107(01)00292-5
P407
P577
2002-01-01T00:00:00Z