Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia.
about
Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestineE-cadherin is required for intestinal morphogenesis in the mouseElevated ASCL2 expression in breast cancer is associated with the poor prognosis of patients.The Research Progress on Intestinal Stem Cells and Its Relationship with Intestinal Microbiota.Musashi1 expression cells derived from mouse embryonic stem cells can be enriched in side population isolated by fluorescence activated cell sorter.Progenitor expansion in apc mutants is mediated by Jak/Stat signalingSynthetic lethal screen of an EGFR-centered network to improve targeted therapies.Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells.Novel translational strategies in colorectal cancer research.Integrative investigation on breast cancer in ER, PR and HER2-defined subgroups using mRNA and miRNA expression profiling.Post-translational glycoprotein modifications regulate colon cancer stem cells and colon adenoma progression in Apc(min/+) mice through altered Wnt receptor signaling.MicroRNA-200 (miR-200) cluster regulation by achaete scute-like 2 (Ascl2): impact on the epithelial-mesenchymal transition in colon cancer cells.Identification of upstream regulators for prognostic expression signature genes in colorectal cancer.Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells.A WNT/p21 circuit directed by the C-clamp, a sequence-specific DNA binding domain in TCFs.Elevated ASCL2 expression is associated with metastasis of osteosarcoma and predicts poor prognosis of the patientsConstrained Score Statistics Identify Genetic Variants Interacting with Multiple Risk Factors in Barrett's EsophagusBmi-1 promotes the invasion and migration of colon cancer stem cells through the downregulation of E-cadherin.MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications.Molecular mechanisms of genomic imprinting and clinical implications for cancer.Achaete scute-like 2 suppresses CDX2 expression and inhibits intestinal neoplastic epithelial cell differentiation.Roles of Wnt Target Genes in the Journey of Cancer Stem CellsIntestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.Silibinin strongly inhibits the growth kinetics of colon cancer stem cell-enriched spheroids by modulating interleukin 4/6-mediated survival signals.Comprehensive analysis of β-catenin target genes in colorectal carcinoma cell lines with deregulated Wnt/β-catenin signaling.Aberrant upregulation of ASCL2 by promoter demethylation promotes the growth and resistance to 5-fluorouracil of gastric cancer cells.Elevated expression of ASCL2 is an independent prognostic indicator in lung squamous cell carcinoma.The role of Pygo2 for Wnt/ß-catenin signaling activity during intestinal tumor initiation and progression.PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition.In situ validation of an intestinal stem cell signature in colorectal cancer.Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue-specific manner.Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.Wnt Signalling in Intestinal Stem Cells: Lessons from Mice and Flies.SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis.Wnt Signalling in Gastrointestinal Epithelial Stem Cells.Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine.Proteomic Techniques in Colorectal Cancer ResearchTales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancerASCL2 expression contributes to gastric tumor migration and invasion by downregulating miR223 and inducing EMT
P2860
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P2860
Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@ast
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@en
Achaete-scute like 2
@nl
type
label
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@ast
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@en
Achaete-scute like 2
@nl
prefLabel
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@ast
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@en
Achaete-scute like 2
@nl
P2093
P356
P1433
P1476
Achaete-scute like 2 (ascl2) i ...... lated in intestinal neoplasia.
@en
P2093
Chalasani S
Grabsch HI
Maughan NJ
P2888
P304
P356
10.1038/SJ.ONC.1209382
P407
P577
2006-03-27T00:00:00Z
P5875
P6179
1006487212