Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells.
about
Murine homologue of the human KIAA1199 is implicated in hyaluronan binding and depolymerizationUnraveling the role of KIAA1199, a novel endoplasmic reticulum protein, in cancer cell migrationKIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerizationHypoxia promotes colon cancer dissemination through up-regulation of cell migration-inducing protein (CEMIP)Keratin23 (KRT23) knockdown decreases proliferation and affects the DNA damage response of colon cancer cellsFunctional proteomic analysis reveals the involvement of KIAA1199 in breast cancer growth, motility and invasiveness.KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer.Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.KIAA1199 interacts with glycogen phosphorylase kinase β-subunit (PHKB) to promote glycogen breakdown and cancer cell survival.Transcriptional and epigenetic regulation of KIAA1199 gene expression in human breast cancerNF-κB-induced KIAA1199 promotes survival through EGFR signalling.Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors.CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling.Association between KIAA1199 overexpression and tumor invasion, TNM stage, and poor prognosis in colorectal cancer.KIAA1199 as a potential diagnostic biomarker of rheumatoid arthritis related to angiogenesis.Transcriptomic profiles differentiate normal rectal epithelium and adenocarcinoma.Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapiesInduction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival.Distinct Expression Pattern of a Deafness Gene, KIAA1199, in a Primate CochleaCrosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis.Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial NeoplasiaKIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer.Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma.N-Terminal signal sequence is required for cellular trafficking and hyaluronan-depolymerization of KIAA1199.The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.Elevated expression of ASCL2 is an independent prognostic indicator in lung squamous cell carcinoma.Central Role of CEMIP in Tumorigenesis and Its Potential as Therapeutic Target.Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts.Expression and function of microRNA-188-5p in activated rheumatoid arthritis synovial fibroblasts.Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer.DNA Methylation Profiling Reveals the Change of Inflammation-Associated ZC3H12D in Leukoaraiosis.Knockdown of KIAA1199 attenuates growth and metastasis of hepatocellular carcinoma
P2860
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P2860
Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Repression of KIAA1199 attenua ...... eration of colon cancer cells.
@ast
Repression of KIAA1199 attenua ...... eration of colon cancer cells.
@en
type
label
Repression of KIAA1199 attenua ...... eration of colon cancer cells.
@ast
Repression of KIAA1199 attenua ...... eration of colon cancer cells.
@en
prefLabel
Repression of KIAA1199 attenua ...... eration of colon cancer cells.
@ast
Repression of KIAA1199 attenua ...... eration of colon cancer cells.
@en
P2093
P2860
P50
P356
P1476
Repression of KIAA1199 attenua ...... feration of colon cancer cells
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.2011.268
P407
P577
2011-07-19T00:00:00Z