Determination of the two-dimensional interaction rate constants of a cytokine receptor complex.
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Structural basis of TLR5-flagellin recognition and signalingReceptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signalingRedirecting cell-type specific cytokine responses with engineered interleukin-4 superkinesStructure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunityStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling.Fundamental aspects of protein-protein association kineticsUnderstanding cytokine and growth factor receptor activation mechanisms.Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity.Receptor density is key to the alpha2/beta interferon differential activities.Microcantilever-Based Label-Free Characterization of Temperature-Dependent Biomolecular Affinity Binding.Cytokine-receptor interactions as drug targets.NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site.Modeling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion.Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret.Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments.Control of growth factor networks by heparan sulfate proteoglycans.The stability of the ternary interferon-receptor complex rather than the affinity to the individual subunits dictates differential biological activities.
P2860
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P2860
Determination of the two-dimensional interaction rate constants of a cytokine receptor complex.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Determination of the two-dimen ...... f a cytokine receptor complex.
@ast
Determination of the two-dimen ...... f a cytokine receptor complex.
@en
Determination of the two-dimen ...... f a cytokine receptor complex.
@nl
type
label
Determination of the two-dimen ...... f a cytokine receptor complex.
@ast
Determination of the two-dimen ...... f a cytokine receptor complex.
@en
Determination of the two-dimen ...... f a cytokine receptor complex.
@nl
prefLabel
Determination of the two-dimen ...... f a cytokine receptor complex.
@ast
Determination of the two-dimen ...... f a cytokine receptor complex.
@en
Determination of the two-dimen ...... f a cytokine receptor complex.
@nl
P2093
P2860
P1433
P1476
Determination of the two-dimen ...... f a cytokine receptor complex.
@en
P2093
Jacob Piehler
Martynas Gavutis
Peter Lamken
P2860
P304
P356
10.1529/BIOPHYSJ.105.072546
P407
P577
2006-02-10T00:00:00Z