Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme. - Wikidata - wikimedia - TriplyDB

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

http://www.wikidata.org/entity/Q34539649

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Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme The evolutionary portrait of metazoan NAD salvage A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein Structure of Salmonella typhimurium OMP Synthase in a Complete Substrate Complex Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine Biochemical characterization of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv and inhibition of its activity by pyrazinamide Structural basis for resistance to diverse classes of NAMPT inhibitors Insulin resistance in chronic kidney disease: a systematic review.NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples.Structure-activity relationship analysis of cytotoxic cyanoguanidines: selection of CHS 828 as candidate drug Identification of novel pathogenic copy number aberrations in multiple myeloma: the Malaysian context Adipose tissue NAD+ biology in obesity and insulin resistance: From mechanism to therapy "Clocks" in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery.P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage The NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants.Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene.The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance Is PBEF/visfatin/Nampt an authentic adipokine relevant to the metabolic syndrome?Nicotinamide phosphoribosyltransferase is essential for interleukin-1beta-mediated dedifferentiation of articular chondrocytes via SIRT1 and extracellular signal-regulated kinase (ERK) complex signaling Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1α in human dopaminergic neurons via Sirtuin-1.Nicotinamide Phosphoribosyltransferase in Human Diseases.SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice.Potential role of leptin, adiponectin and three novel adipokines--visfatin, chemerin and vaspin--in chronic hepatitis.Unique Toll-Like Receptor 4 Activation by NAMPT/PBEF Induces NFκB Signaling and Inflammatory Lung Injury Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt Adipokines and melanocortins in the hepatic manifestation of metabolic syndrome: nonalcoholic fatty liver disease.Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin-6/STAT3 signaling mechanism.Deacetylation by SIRT1 Reprograms Inflammation and Cancer Pre-B cell colony enhancing factor (PBEF), a cytokine with multiple physiological functions.The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing.Nicotinamide phosphoribosyltransferase (Nampt): a link between NAD biology, metabolism, and diseases.Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes.Nampt: linking NAD biology, metabolism and cancer.

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P2860

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

http://www.wikidata.org/entity/Q34539649

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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type

label

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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prefLabel

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

@ast

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

@en

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme.

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Nature Structural & Molecular Biology

P1476

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme

@en

P2093

Javier R Revollo

http://www.w3.org/2001/XMLSchema#string

Poonam Bheda

http://www.w3.org/2001/XMLSchema#string

Shin-ichiro Imai

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Tao Wang

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Xiangbin Zhang

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P2860

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase

Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

Conversion of a cosubstrate to an inhibitor: phosphorylation mutants of nicotinic acid phosphoribosyltransferase.

Catalytic triads and their relatives

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum.

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.

Comparison of sequence profiles. Strategies for structural predictions using sequence information.

P2888

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661-662

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scholarly article

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10.1038/NSMB1114

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7

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13

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Cynthia Wolberger

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2006-06-18T00:00:00Z

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16783373

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Nicotinamide phosphoribosyltransferase