The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance
about
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promotersSIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.Sirtuins Link Inflammation and MetabolismThe role of mammalian sirtuins in the regulation of metabolism, aging, and longevityAutophagy in cardiovascular biologyModulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activityImmune Cell Regulatory Pathways Unexplored as Host-Directed Therapeutic Targets for Mycobacterium tuberculosis: An Opportunity to Apply Precision Medicine Innovations to Infectious DiseasesSynergistic interactions between HDAC and sirtuin inhibitors in human leukemia cellsMammalian sirtuins: biological insights and disease relevanceDetection of cerebral NAD(+) by in vivo (1)H NMR spectroscopy.Detection of cerebral NAD+ in humans at 7T.A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis.Genistein Ameliorates Ischemia/Reperfusion-Induced Renal Injury in a SIRT1-Dependent Manner.Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathwayCircadian rhythms and metabolic syndrome: from experimental genetics to human disease.It takes two to tango: NAD+ and sirtuins in aging/longevity control"Clocks" in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and agingThe NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control.Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasmaSIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK.Renal protective effect of sirtuin 1Nicotinamide phosphoribosyltransferase may be involved in age-related brain diseases.NAD+-dependent SIRT1 deacetylase participates in epigenetic reprogramming during endotoxin tolerance.Neuronal NAMPT is released after cerebral ischemia and protects against white matter injuryLeucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre-B cell colony (PBEF)/visfatin linking obesity and inflammation in humans.Dissecting systemic control of metabolism and aging in the NAD World: the importance of SIRT1 and NAMPT-mediated NAD biosynthesis.Nicotinamide Phosphoribosyltransferase in Human Diseases.Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.High glucose promotes gastric cancer chemoresistance in vivo and in vitroSirtuins and their relevance to the kidney.Association of Nicotinamide Phosphoribosyltransferase (NAMPT) Gene Polymorphisms and of Serum NAMPT Levels with Dilated Cardiomyopathy in a Chinese Population.NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity.Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1.Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.Nature's Timepiece-Molecular Coordination of Metabolism and Its Impact on Aging.Involvement of Daphnia pulicaria Sir2 in regulating stress response and lifespanThe dynamic regulation of NAD metabolism in mitochondria.Effects of hyperglycemia and aging on nuclear sirtuins and DNA damage of mouse hepatocytesCD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cellsNampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling.
P2860
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P2860
The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The NAD World: a new systemic ...... ynthesis, and their importance
@ast
The NAD World: a new systemic ...... ynthesis, and their importance
@en
The NAD World: a new systemic ...... ynthesis, and their importance
@nl
type
label
The NAD World: a new systemic ...... ynthesis, and their importance
@ast
The NAD World: a new systemic ...... ynthesis, and their importance
@en
The NAD World: a new systemic ...... ynthesis, and their importance
@nl
prefLabel
The NAD World: a new systemic ...... ynthesis, and their importance
@ast
The NAD World: a new systemic ...... ynthesis, and their importance
@en
The NAD World: a new systemic ...... ynthesis, and their importance
@nl
P2860
P1476
The NAD World: a new systemic ...... ynthesis, and their importance
@en
P2093
Shin-Ichiro Imai
P2860
P2888
P356
10.1007/S12013-008-9041-4
P577
2009-01-01T00:00:00Z
P5875
P6179
1012461703