A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells. - Wikidata - wikimedia - TriplyDB

A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.

A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.

http://www.wikidata.org/entity/Q34540424

about

Oridonin inhibits tumor growth and metastasis through anti-angiogenesis by blocking the Notch signaling Dual targeted therapy with p53 siRNA and Epigallocatechingallate in a triple negative breast cancer cell model Identification of differently expressed genes and small molecule drugs for Tetralogy of Fallot by bioinformatics strategy.A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway A network model for angiogenesis in ovarian cancer.Inhibition of breast cancer progression by a novel histone deacetylase inhibitor, LW479, by down-regulating EGFR expression.A novel synthetic small molecule YF-452 inhibits tumor growth through antiangiogenesis by suppressing VEGF receptor 2 signaling.Synthesis and mechanisms of action of novel harmine derivatives as potential antitumor agents.Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways.Clinical antiangiogenic effect of recombinant adenovirus-p53 combined with hyperthermia for advanced cancer.Harmine combined with paclitaxel inhibits tumor proliferation and induces apoptosis through down-regulation of cyclooxygenase-2 expression in gastric cancer.DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis.T11TS Treatment Augments Apoptosis of Glioma Associated Brain Endothelial Cells, Hint Toward Anti-Angiogenic Action in Glioma.Synthesis of novel heterocyclic ring-fused 18β-glycyrrhetinic acid derivatives with antitumor and antimetastatic activity.Validating antimetastatic effects of natural products in an engineered microfluidic platform mimicking tumor microenvironment.High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer.Changes in aminoacidergic and monoaminergic neurotransmission in the hippocampus and amygdala of rats after ayahuasca ingestion.The inhibitory effects of compound Muniziqi granule against B16 cells and harmine induced autophagy and apoptosis by inhibiting Akt/mTOR pathway.Inhibition of histone deacetylases sensitizes EGF receptor-TK inhibitor-resistant non-small-cell lung cancer cells to erlotinib in vitro and in vivo.Harmine enhances type H vessel formation and prevents bone loss in ovariectomized mice.Potent Antitumor Effects of a Combination of Three Nutraceutical Compounds

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P2860

A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells.

http://www.wikidata.org/entity/Q34540424

description

2012 nî lūn-bûn

@nan

2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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type

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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A natural small molecule harmi ...... n of p53 in endothelial cells.

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Dali Li

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Dong Zhai

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Fujun Dai

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Li Huang

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Li Lai

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Tao Zhang

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Xiufeng Pang

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Yajuan Song

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Yanmin Dong

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Zhengfang Yi

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P2860

Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3

Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function

Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme

β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites

NAHA, a novel hydroxamic acid-derivative, inhibits growth and angiogenesis of breast cancer in vitro and in vivo

Modes of p53 regulation

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