RNA structure of trinucleotide repeats associated with human neurological diseases. - Wikidata - wikimedia - TriplyDB

RNA structure of trinucleotide repeats associated with human neurological diseases.

RNA structure of trinucleotide repeats associated with human neurological diseases.

http://www.wikidata.org/entity/Q34542108

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Muscleblind proteins regulate alternative splicing Facile FMR1 mRNA structure regulation by interruptions in CGG repeats Structural studies of CNG repeats Mechanisms of RNA-induced toxicity in CAG repeat disorders Thermodynamic characterization of tandem mismatches found in naturally occurring RNA Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome Crystallographic characterization of CCG repeats Progress and challenges for chemical probing of RNA structure inside living cells RNA-mediated pathogenic mechanisms in polyglutamine diseases and amyotrophic lateral sclerosis G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome Drosophila as an In Vivo Model for Human Neurodegenerative Disease Computational investigation of RNA CUG repeats responsible for myotonic dystrophy 1 Mechanistic determinants of MBNL activity Controlling the specificity of modularly assembled small molecules for RNA via ligand module spacing: targeting the RNAs that cause myotonic muscular dystrophy The role of flexibility in the rational design of modularly assembled ligands targeting the RNAs that cause the myotonic dystrophies MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing.Oligonucleotide-based strategies to combat polyglutamine diseases.Long tract of untranslated CAG repeats is deleterious in transgenic mice Distinctive structural motifs of RNA G-quadruplexes composed of AGG, CGG and UGG trinucleotide repeats.Two high-throughput screening assays for aberrant RNA-protein interactions in myotonic dystrophy type 1.Structural basis of microRNA length variety.The structural basis of myotonic dystrophy from the crystal structure of CUG repeats A pathogenic mechanism in Huntington's disease involves small CAG-repeated RNAs with neurotoxic activity.RNA-protein interactions in unstable microsatellite diseases.Tandem repeats discovery service (TReaDS) applied to finding novel cis-acting factors in repeat expansion diseases.MBNL proteins and their target RNAs, interaction and splicing regulation.A superfolding Spinach2 reveals the dynamic nature of trinucleotide repeat-containing RNA Initiation of translation of the FMR1 mRNA Occurs predominantly through 5'-end-dependent ribosomal scanning Reversal of RNA missplicing and myotonia after muscleblind overexpression in a mouse poly(CUG) model for myotonic dystrophy.Features of modularly assembled compounds that impart bioactivity against an RNA target.A GAG trinucleotide-repeat polymorphism in the gene for glutathione biosynthetic enzyme, GCLC, affects gene expression through translation Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.Selective inhibition of MBNL1-CCUG interaction by small molecules toward potential therapeutic agents for myotonic dystrophy type 2 (DM2)Structures of trinucleotide repeats in human transcripts and their functional implications.Genes and pathways affected by CAG-repeat RNA-based toxicity in Drosophila Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target Structural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)Repetitive sequences that shape the human transcriptome.RNA Structures as Mediators of Neurological Diseases and as Drug Targets.

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P2860

RNA structure of trinucleotide repeats associated with human neurological diseases.

http://www.wikidata.org/entity/Q34542108

description

2003 nî lūn-bûn

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2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

RNA structure of trinucleotide repeats associated with human neurological diseases.

@ast

RNA structure of trinucleotide repeats associated with human neurological diseases.

@en

RNA structure of trinucleotide repeats associated with human neurological diseases.

@nl

type

label

RNA structure of trinucleotide repeats associated with human neurological diseases.

@ast

RNA structure of trinucleotide repeats associated with human neurological diseases.

@en

RNA structure of trinucleotide repeats associated with human neurological diseases.

@nl

prefLabel

RNA structure of trinucleotide repeats associated with human neurological diseases.

@ast

RNA structure of trinucleotide repeats associated with human neurological diseases.

@en

RNA structure of trinucleotide repeats associated with human neurological diseases.

@nl

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P1433

Nucleic Acids Research

P1476

RNA structure of trinucleotide repeats associated with human neurological diseases.

@en

P2093

Jacek Krol

http://www.w3.org/2001/XMLSchema#string

Krzysztof Sobczak

http://www.w3.org/2001/XMLSchema#string

Mateusz de Mezer

http://www.w3.org/2001/XMLSchema#string

P2860

Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy

A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells

Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing

The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure

Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms

In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts

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5469-5482

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scholarly article

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10.1093/NAR/GKG766

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19

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31

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Gracjan Michlewski

Włodzimierz Krzyżosiak

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2003-10-01T00:00:00Z

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14500809

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206466

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