Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
about
STRAD pseudokinases regulate axogenesis and LKB1 stabilityIdentification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodiesSTE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cellsSgt1 acts via an LKB1/AMPK pathway to establish cortical polarity in larval neuroblasts.High prevalence of germline STK11 mutations in Hungarian Peutz-Jeghers Syndrome patients.Endurance training increases LKB1 and MO25 protein but not AMP-activated protein kinase kinase activity in skeletal muscle.Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function.Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.The LKB1 tumor suppressor as a biomarker in mouse and human tissues.Lipopolysaccharides Promote S-Nitrosylation and Proteasomal Degradation of Liver Kinase B1 (LKB1) in Macrophages in VivoCombined HSP90 and kinase inhibitor therapy: Insights from The Cancer Genome Atlas.The double edge of the HSP90-CDC37 chaperone machinery: opposing determinants of kinase stability and activityAMP-activated protein kinase (AMPK)-dependent and -independent pathways regulate hypoxic inhibition of transepithelial Na+ transport across human airway epithelial cells.A genome-wide RNAi screen for enhancers of par mutants reveals new contributors to early embryonic polarity in Caenorhabditis elegans.Liver kinase B1 expression promotes phosphatase activity and abrogation of receptor tyrosine kinase phosphorylation in human cancer cells.Targeting the LKB1 tumor suppressor.The LKB1 complex-AMPK pathway: the tree that hides the forestLKB1 Tumor Suppressor: Therapeutic Opportunities Knock when LKB1 Is Inactivated.Resveratrol-Induced AMP-Activated Protein Kinase Activation Is Cell-Type Dependent: Lessons from Basic Research for Clinical Application.LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.Regulation of stability of cyclin-dependent kinase CDK11p110 and a caspase-processed form, CDK11p46, by Hsp90.DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging.The role of DNA-PK in aging and energy metabolism.Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.Hsp90 Recognizes a Common Surface on Client Kinases
P2860
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P2860
Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@ast
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@en
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@nl
type
label
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@ast
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@en
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@nl
prefLabel
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@ast
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@en
Stability of the Peutz-Jeghers ...... ecular chaperones Hsp90/Cdc37.
@nl
P2093
P356
P1433
P1476
Stability of the Peutz-Jeghers ...... lecular chaperones Hsp90/Cdc37
@en
P2093
Hélène Gaude
Jean-Pierre Rouault
Laurence Fournier
Marc Billaud
Pascale Nony
P2888
P304
P356
10.1038/SJ.ONC.1207179
P407
P577
2003-12-01T00:00:00Z
P5875
P6179
1030490766