MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer - Wikidata - wikimedia - TriplyDB

MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer

MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer

http://www.wikidata.org/entity/Q34555709

about

Mucins in cancer: function, prognosis and therapy Adenoviral vectors for prodrug activation-based gene therapy for cancer Cooperative interaction between the MUC1-C oncoprotein and the Rab31 GTPase in estrogen receptor-positive breast cancer cells MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect.MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients Cooperativity of the MUC1 oncoprotein and STAT1 pathway in poor prognosis human breast cancer.Mucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.Targeting the oncogenic MUC1-C protein inhibits mutant EGFR-mediated signaling and survival in non-small cell lung cancer cells Functional targeting of the MUC1 oncogene in human cancers MUC1-C confers EMT and KRAS independence in mutant KRAS lung cancer cells Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells.A pilot study of MUC-1/CEA/TRICOM poxviral-based vaccine in patients with metastatic breast and ovarian cancer.Mucins in the pathogenesis of breast cancer: implications in diagnosis, prognosis and therapy.A monoclonal antibody against the oncogenic mucin 1 cytoplasmic domain Robust meta-analysis of gene expression using the elastic net.MUC1-C activates the TAK1 inflammatory pathway in colon cancer Gene expression of circulating tumour cells and its correlation with tumour stage in breast cancer patients.Integrating the multiple dimensions of genomic and epigenomic landscapes of cancer.Low miR-145 silenced by DNA methylation promotes NSCLC cell proliferation, migration and invasion by targeting mucin 1.Prognostic significance of membrane-associated mucins 1 and 4 in gastric adenocarcinoma.Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.The generation and analyses of a novel combination of recombinant adenovirus vaccines targeting three tumor antigens as an immunotherapeutic.Expression of underglycosylated MUC1 antigen in cancerous and adjacent normal breast tissues.Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas.Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model.MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.Natural and Induced Humoral Responses to MUC1.Direct targeting of the mucin 1 oncoprotein blocks survival and tumorigenicity of human breast carcinoma cells.Maintenance and consolidation therapy in patients with unresectable stage III/IV non-small cell lung cancer.Glycosylation alterations in lung and brain cancer.Downregulation of lysosomal and further gene expression characterization in lung cancer patients with bone metastasis.Update on Mucin-1 immunotherapy in cancer: a clinical perspective.MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner.Critical roles of mucin-1 in sensitivity of lung cancer cells to tumor necrosis factor-alpha and dexamethasone.Lewis(y) antigen promotes the progression of epithelial ovarian cancer by stimulating MUC1 expression.MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.

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P2860

MUC1-induced transcriptional programs associated with tumorigenesis predict outcome in breast and lung cancer

http://www.wikidata.org/entity/Q34555709

description

2009 nî lūn-bûn

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2009 թուականի Մարտին հրատարակուած գիտական յօդուած

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2009 թվականի մարտին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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type

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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Cancer Research

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MUC1-induced transcriptional p ...... come in breast and lung cancer

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P2093

Dhara M MacDermed

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Donald W Kufe

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Lei Huang

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Michael A Beckett

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Nikolai N Khodarev

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Sean P Pitroda

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P2860

Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response

Significance analysis of microarrays applied to the ionizing radiation response

The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts

Cell surface-associated mucins in signal transduction

MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin

Cell-associated episialin is a complex containing two proteins derived from a common precursor

Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation.

CA 15-3 is predictive of response and disease recurrence following treatment in locally advanced breast cancer

Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival.

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2833-2837

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10.1158/0008-5472.CAN-08-4513

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7

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69

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Ralph Weichselbaum

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19318547

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3034477

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