Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration. - Wikidata - wikimedia - TriplyDB

Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.

Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.

http://www.wikidata.org/entity/Q34565579

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Management of neovascular age-related macular degeneration: current state-of-the-art care for optimizing visual outcomes and therapies in development Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix components Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysis The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve.Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.The autolysis of human HtrA1 is governed by the redox state of its N-terminal domain Variants at chromosome 10q26 locus and the expression of HTRA1 in the retina.FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.Specific correlation between the major chromosome 10q26 haplotype conferring risk for age-related macular degeneration and the expression of HTRA1 Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics.Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria Genetics of age-related macular degeneration: current concepts, future directions.Copy number variations in candidate genes in neovascular age-related macular degeneration.Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world.Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics.Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degeneration Association of Htra1 gene polymorphisms with the risk of developing AMD in Iranian population Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.Complement factor H and LOC387715/ARMS2/HTRA1 variant's frequencies and phenotypic associations in neovascular age-related macular degeneration, a pilot study.Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel.The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples.Molecular pathology of age-related macular degeneration Biologically active fibronectin fragments stimulate release of MCP-1 and catabolic cytokines from murine retinal pigment epithelium Cumulative association between age-related macular degeneration and less studied genetic variants in PLEKHA1/ARMS2/HTRA1: a meta and gene-cluster analysis Comprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.Inflammatory mediators and angiogenic factors in choroidal neovascularization: pathogenetic interactions and therapeutic implications.Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration.Overexpression of HTRA1 leads to down-regulation of fibronectin and functional changes in RF/6A cells and HUVECs.Genetics of age-related macular degeneration (AMD).Genetic association study of age-related macular degeneration in the Spanish population.ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity.Myopia in Chinese families shows linkage to 10q26.13.

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P2860

Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.

http://www.wikidata.org/entity/Q34565579

description

2007 nî lūn-bûn

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2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Alleles in the HtrA serine pep ...... -related macular degeneration.

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Amanda J Harring

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Antonio Capone

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Fei Ji

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Ivana K Kim

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Joan W Miller

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Jurg Ott

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Margaret M Deangelis

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Meredith O Sweeney

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Scott Adams

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P2860

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

Susceptibility genes for age-related maculopathy on chromosome 10q26.

Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration

Complement factor H polymorphism in age-related macular degeneration

The structure of haplotype blocks in the human genome

Haploview: analysis and visualization of LD and haplotype maps

Extremely discordant sib-pair study design to determine risk factors for neovascular age-related macular degeneration

Complement factor H variant increases the risk of age-related macular degeneration

HTRA1 promoter polymorphism in wet age-related macular degeneration

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