Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.
about
Management of neovascular age-related macular degeneration: current state-of-the-art care for optimizing visual outcomes and therapies in developmentOverexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix componentsSynonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysisThe NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degenerationConvergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approachApplication of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve.Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degenerationSpontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.The autolysis of human HtrA1 is governed by the redox state of its N-terminal domainVariants at chromosome 10q26 locus and the expression of HTRA1 in the retina.FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression.Specific correlation between the major chromosome 10q26 haplotype conferring risk for age-related macular degeneration and the expression of HTRA1Identifying subtypes of patients with neovascular age-related macular degeneration by genotypic and cardiovascular risk characteristics.Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondriaGenetics of age-related macular degeneration: current concepts, future directions.Copy number variations in candidate genes in neovascular age-related macular degeneration.Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.Ancestry of the Timorese: age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world.Genetic mechanisms and age-related macular degeneration: common variants, rare variants, copy number variations, epigenetics, and mitochondrial genetics.Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration.Clinical validation of a genetic model to estimate the risk of developing choroidal neovascular age-related macular degenerationAssociation of Htra1 gene polymorphisms with the risk of developing AMD in Iranian populationAge-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.Comprehensive analysis of CRP, CFH Y402H and environmental risk factors on risk of neovascular age-related macular degeneration.Complement factor H and LOC387715/ARMS2/HTRA1 variant's frequencies and phenotypic associations in neovascular age-related macular degeneration, a pilot study.Sequence variants in HTRA1 and LOC387715/ARMS2 and phenotype and response to photodynamic therapy in neovascular age-related macular degeneration in populations from Israel.The HtrA1 promoter polymorphism, smoking, and age-related macular degeneration in multiple case-control samples.Molecular pathology of age-related macular degenerationBiologically active fibronectin fragments stimulate release of MCP-1 and catabolic cytokines from murine retinal pigment epitheliumCumulative association between age-related macular degeneration and less studied genetic variants in PLEKHA1/ARMS2/HTRA1: a meta and gene-cluster analysisComprehensive analysis of complement factor H and LOC387715/ARMS2/HTRA1 variants with respect to phenotype in advanced age-related macular degeneration.Inflammatory mediators and angiogenic factors in choroidal neovascularization: pathogenetic interactions and therapeutic implications.Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration.Overexpression of HTRA1 leads to down-regulation of fibronectin and functional changes in RF/6A cells and HUVECs.Genetics of age-related macular degeneration (AMD).Genetic association study of age-related macular degeneration in the Spanish population.ER stress-induced aggresome trafficking of HtrA1 protects against proteotoxicity.Myopia in Chinese families shows linkage to 10q26.13.
P2860
Q26824335-13980D10-C108-427E-A4D1-0BF65E7C70B2Q28741873-0C516ADF-C881-4FC8-B35E-FB79C8FDA4A5Q30378420-C848FF6E-5BC6-4DD6-BA2E-DF6E5B49C418Q32125469-D7636669-536B-44DB-9C42-C3242DC92E44Q33341495-AAB8500B-77EC-49F7-8AA1-477371724174Q33507197-5161734C-832B-4EC6-BF59-48391F21C299Q33526253-8CA810A3-B738-465E-BC96-7B6C95422FACQ33530081-A82C76CC-559F-43F2-9E37-3FAA0FB39FA6Q33761013-52711629-5DBC-46A9-BFAB-91A4D66E15C7Q33792759-3DB0E9DF-678A-48B3-9483-1D9C7530FBF1Q33803810-1520D485-6608-4ACB-9AE1-2582DD96B8B6Q33816926-98033744-8CA9-47CC-A1CC-06BB0DBD6738Q33822183-0F439FC1-BF76-4FE6-B31C-F647BBC16B6CQ33935415-9BC99B57-8F5E-415B-ACE4-3203FC53E33EQ34402769-F7AE2C08-C1FE-430C-A6C0-22C1B86002E2Q34565573-12C4E424-752B-4AC2-8E9B-AA9BA05D91B5Q35027522-D7D9F96C-AD21-4823-9C08-BBCBC6C439F6Q35118257-24AB465F-B811-4AF9-A33A-CB1738E76210Q35833700-F4675286-3E5E-4B08-9D2E-F8EC07034574Q36405448-A6A3327E-06AB-4AE2-85C7-9B94CCC61EEEQ36475159-BE6C23A5-759F-4220-BE19-FB24AB0B8516Q36477011-767A7863-296D-4194-BA3F-D1AF13317E44Q36589584-DC41D0D1-2406-4316-9BDE-618D31BD75E8Q36826856-058C9942-2B00-4BCD-A3FF-A30F1B1D1995Q36836558-0D885341-9784-432D-83D0-A273C5116E8DQ36938286-DDF71C75-D279-4273-93A1-96A3DE81CCCAQ37000931-F53530DD-C67A-45D9-A338-C7EC9E68E5ADQ37030323-8AED8DF3-5200-4F35-A911-0C10F905FC39Q37273740-6B2E3CC4-75E9-4563-A419-A109700E9F07Q37369684-11206B3A-6E0B-40D2-8986-5A360F2173D9Q37394599-948A60C6-9C00-495A-ACB0-5833B96F30C5Q37455410-47CA534A-D0A8-435F-AE23-7CF64C1E36EAQ37792817-71F73973-0B30-4337-8A4F-9800FD7CF692Q38030051-A0ECAEF4-C6DC-43A1-854B-C571E8CBC3F6Q39261579-D35B7B63-3D3F-49AD-8CC4-6F8435778494Q40064848-F7D1F3A9-66DF-4F0F-8001-7C966D9393ADQ47105600-D8A0E555-712D-4418-9FD5-312529B9E3B6Q47189539-593B817D-5173-4A7C-9876-DEAC09A8C117Q49218541-E2527532-FA39-42AB-AB28-234AD2F90FBA
P2860
Alleles in the HtrA serine peptidase 1 gene alter the risk of neovascular age-related macular degeneration.
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Alleles in the HtrA serine pep ...... -related macular degeneration.
@ast
Alleles in the HtrA serine pep ...... -related macular degeneration.
@en
Alleles in the HtrA serine pep ...... -related macular degeneration.
@nl
type
label
Alleles in the HtrA serine pep ...... -related macular degeneration.
@ast
Alleles in the HtrA serine pep ...... -related macular degeneration.
@en
Alleles in the HtrA serine pep ...... -related macular degeneration.
@nl
prefLabel
Alleles in the HtrA serine pep ...... -related macular degeneration.
@ast
Alleles in the HtrA serine pep ...... -related macular degeneration.
@en
Alleles in the HtrA serine pep ...... -related macular degeneration.
@nl
P2093
P2860
P1433
P1476
Alleles in the HtrA serine pep ...... -related macular degeneration.
@en
P2093
Amanda J Harring
Antonio Capone
Ivana K Kim
Joan W Miller
Margaret M Deangelis
Margaux A Morrison
Meredith O Sweeney
Scott Adams
P2860
P304
1209-1215.e7
P356
10.1016/J.OPHTHA.2007.10.032
P577
2007-12-27T00:00:00Z