TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells - Wikidata - wikimedia - TriplyDB

TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells

TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells

http://www.wikidata.org/entity/Q34568463

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Modeling the study of DNA damage responses in mice Double-strand break repair on sex chromosomes: challenges during male meiotic prophase TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.SWI/SNF complexes are required for full activation of the DNA-damage response.TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.Expression of TopBP1 in hereditary breast cancer Association between the c.*229C>T polymorphism of the topoisomerase IIβ binding protein 1 (TopBP1) gene and breast cancer.cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.DNA Damage Reduces the Quality, but Not the Quantity of Human Papillomavirus 16 E1 and E2 DNA Replication TopBP1 contributes to the chemoresistance in non-small cell lung cancer through upregulation of p53 TopBP1 deficiency impairs V(D)J recombination during lymphocyte development.The epigenetic modifier Fam208a is required to maintain epiblast cell fitness.Levels of the E2 interacting protein TopBP1 modulate papillomavirus maintenance stage replication.Systems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansion.Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors.Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation.DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line.HUS1 regulates in vivo responses to genotoxic chemotherapies.AIMP3 Deletion Induces Acute Radiation Syndrome-like Phenotype in Mice Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling AIMP3 depletion causes genome instability and loss of stemness in mouse embryonic stem cells The ATR-Activation Domain of TopBP1 Is Required for the Suppression of Origin Firing during the S Phase

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TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells

http://www.wikidata.org/entity/Q34568463

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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type

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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prefLabel

TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

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JBC.M110.189704

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Journal of Biological Chemistry

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TopBP1 deficiency causes an ea ...... ar senescence in primary cells

@en

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Chang Hwan Jeon

http://www.w3.org/2001/XMLSchema#string

Deog Su Hwang

http://www.w3.org/2001/XMLSchema#string

Eun Ko

http://www.w3.org/2001/XMLSchema#string

Ho Lee

http://www.w3.org/2001/XMLSchema#string

Jeeheon Kang

http://www.w3.org/2001/XMLSchema#string

Kyung Yong Lee

http://www.w3.org/2001/XMLSchema#string

Min Ji Ko

http://www.w3.org/2001/XMLSchema#string

Seo Young Park

http://www.w3.org/2001/XMLSchema#string

Yoon Jeon

http://www.w3.org/2001/XMLSchema#string

P2860

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator

Treslin collaborates with TopBP1 in triggering the initiation of DNA replication

Regulation of TopBP1 oligomerization by Akt/PKB for cell survival

A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair

TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival

Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

Regulation of E2F1 by BRCT domain-containing protein TopBP1

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

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5414-5422

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scholarly article

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10.1074/JBC.M110.189704

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7

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286

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2010-12-13T00:00:00Z

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49675283

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21149450

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3037654

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