PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ. - Wikidata - wikimedia - TriplyDB

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

http://www.wikidata.org/entity/Q34568526

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The E3 ubiquitin ligase Itch and Yap1 have antagonistic roles in the regulation of ASPP2 protein stability Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1 Regulation of TAZ in cancer New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics The Human Adenovirus Type 5 E4orf4 Protein Targets Two Phosphatase Regulators of the Hippo Signaling Pathway Validation of chemical compound library screening for transcriptional co-activator with PDZ-binding motif inhibitors using GFP-fused transcriptional co-activator with PDZ-binding motif Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation.PP1A-mediated dephosphorylation positively regulates YAP2 activity Novel TAZ modulators enhance myogenic differentiation and muscle regeneration.Attenuated expression of apoptosis stimulating protein of p53-2 (ASPP2) in human acute leukemia is associated with therapy failure Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling device KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.ASPP2 links the apical lateral polarity complex to the regulation of YAP activity in epithelial cells.Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1α-TAZ Signaling Pathway in Osteoblasts N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.Regulation of the Hippo pathway and implications for anticancer drug development.(-)-Epicatechin gallate (ECG) stimulates osteoblast differentiation via Runt-related transcription factor 2 (RUNX2) and transcriptional coactivator with PDZ-binding motif (TAZ)-mediated transcriptional activation.Systematic morphological profiling of human gene and allele function via Cell Painting.WW domain interactions regulate the Hippo tumor suppressor pathway.Integrating developmental signals: a Hippo in the (path)way.Okadaic Acid: a tool to study the hippo pathway Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling.Hippo-YAP signaling pathway: A new paradigm for cancer therapy.The Hippo signal transduction network in skeletal and cardiac muscle.The mammalian Hippo pathway: regulation and function of YAP1 and TAZ.Control of Proliferation and Cancer Growth by the Hippo Signaling Pathway.Regulation and function of the TAZ transcription co-activator.PARD3 induces TAZ activation and cell growth by promoting LATS1 and PP1 interaction.A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2.An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.Hepatocyte TAZ/WWTR1 Promotes Inflammation and Fibrosis in Nonalcoholic Steatohepatitis.Integrin-FAK-CDC42-PP1A signaling gnaws at YAP/TAZ activity to control incisor stem cells.TLR3 Mediates Repair and Regeneration of Damaged Neonatal Heart through Glycolysis Dependent YAP1 Regulated miR-152 Expression.Cysteine residues are essential for dimerization of Hippo pathway components YAP2L and TAZ.Regulation of Yki/Yap subcellular localization and Hpo signaling by a nuclear kinase PRP4K.RETRACTED: Analysis of YAP1 and TAZ expression by immunohistochemical staining in malignant mesothelioma and reactive mesothelial cells.

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P2860

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

http://www.wikidata.org/entity/Q34568526

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@ast

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@en

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@nl

type

label

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@ast

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@en

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@nl

prefLabel

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@ast

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@en

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@nl

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P2860

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JBC.M110.194019

P1433

Journal of Biological Chemistry

P1476

PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ.

@en

P2093

Chen-Ying Liu

http://www.w3.org/2001/XMLSchema#string

Kun-Liang Guan

http://www.w3.org/2001/XMLSchema#string

Qun-Ying Lei

http://www.w3.org/2001/XMLSchema#string

Shimin Zhao

http://www.w3.org/2001/XMLSchema#string

Tingting Li

http://www.w3.org/2001/XMLSchema#string

Xianbo Lv

http://www.w3.org/2001/XMLSchema#string

Xin Zhou

http://www.w3.org/2001/XMLSchema#string

Yanping Xu

http://www.w3.org/2001/XMLSchema#string

Yue Xiong

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a novel inhibitor of nuclear factor-kappaB, RelA-associated inhibitor

APCL, a central nervous system-specific homologue of adenomatous polyposis coli tumor suppressor, binds to p53-binding protein 2 and translocates it to the perinucleus

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

Yes-associated protein and p53-binding protein-2 interact through their WW and SH3 domains

ASPP proteins specifically stimulate the apoptotic function of p53

A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome

53BP2S, interacting with insulin receptor substrates, modulates insulin signaling

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

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5558-5566

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scholarly article

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10.1074/JBC.M110.194019

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P407

P433

7

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286

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P577

2010-12-28T00:00:00Z

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21189257

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3037669

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