Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. - Wikidata - wikimedia - TriplyDB

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

http://www.wikidata.org/entity/Q34574484

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Mouse Genetic Models of Human Brain Disorders Neuronal migration abnormalities and its possible implications for schizophrenia Synaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.DISC1: a key lead in studying cortical development and associated brain disorders Improving the predictive value of interventional animal models data The DISC locus in psychiatric illness The NPAS3 gene--emerging evidence for a role in psychiatric illness DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212 Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1 Type III neuregulin-1 is required for normal sensorimotor gating, memory-related behaviors, and corticostriatal circuit components Dixdc1 is a critical regulator of DISC1 and embryonic cortical development The adaptive significance of adult neurogenesis: an integrative approach Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia Mouse genomic variation and its effect on phenotypes and gene regulation Neurodevelopmental animal models of schizophrenia: role in novel drug discovery and development Schizophrenia and Depression Co-Morbidity: What We have Learned from Animal Models.Investigation of gene effects and epistatic interactions between Akt1 and neuregulin 1 in the regulation of behavioral phenotypes and social functions in genetic mouse models of schizophrenia.Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders.Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imaging.Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses.Animal models of schizophrenia.New frontiers in animal research of psychiatric illness Synaptic changes underlying the strengthening of GABA/glycinergic connections in the developing lateral superior olive.Contribution of nonprimate animal models in understanding the etiology of schizophrenia.Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects Development of animal models for schizophrenia.Prepulse inhibition and genetic mouse models of schizophrenia.Animal models of gene-environment interactions in schizophrenia.Impaired Pavlovian fear extinction is a common phenotype across genetic lineages of the 129 inbred mouse strain.The evolution of drug development in schizophrenia: past issues and future opportunities.Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia.Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans.The nucleosome assembly protein TSPYL2 regulates the expression of NMDA receptor subunits GluN2A and GluN2B.Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness From Shortage to Surge: A Developmental Switch in Hippocampal-Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

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P2860

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

http://www.wikidata.org/entity/Q34574484

description

2006 nî lūn-bûn

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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@ast

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@en

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@nl

type

label

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@ast

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@en

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@nl

prefLabel

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@ast

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@en

Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice.

@en

P2093

Hiroko Koike

http://www.w3.org/2001/XMLSchema#string

Joseph A Gogos

http://www.w3.org/2001/XMLSchema#string

Maria Karayiorgou

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Mirna Kvajo

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P Alexander Arguello

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P2860

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

Theta rhythms coordinate hippocampal-prefrontal interactions in a spatial memory task

Disruption of two novel genes by a translocation co-segregating with schizophrenia

Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria

DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

The fractionation of working memory

Complex haplotypes, copy number polymorphisms and coding variation in two recently divergent mouse strains.

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia.

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

Nonsense-mediated decay approaches the clinic.

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3693-3697

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