Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis - Wikidata - wikimedia - TriplyDB

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

http://www.wikidata.org/entity/Q34575334

about

T helper 17 cell heterogeneity and pathogenicity in autoimmune disease Interleukin-23 drives innate and T cell-mediated intestinal inflammation APC-derived cytokines and T cell polarization in autoimmune inflammation Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis Targeting Th17 Cells with Small Molecules and Small Interference RNA Interleukin-23: as a drug target for autoimmune inflammatory diseases The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing Multiple Sclerosis and T Lymphocytes: An Entangled Story Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis Unexpected phenotype of mice lacking Shcbp1, a protein induced during T cell proliferation.Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia-reperfusion injury Beta1 integrins differentially control extravasation of inflammatory cell subsets into the CNS during autoimmunity Ustekinumab in chronic immune-mediated diseases: a review of long term safety and patient improvement Neuroimmunotherapies Targeting T Cells: From Pathophysiology to Therapeutic Applications.IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.Erythropoietin: a potent inducer of peripheral immuno/inflammatory modulation in autoimmune EAE.Development of allergen-induced airway inflammation in the absence of T-bet regulation is dependent on IL-17.RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms.Overexpression of interleukin-23 and interleukin-17 in the lesion of pemphigus vulgaris: a preliminary study.T-bet, a Th1 transcription factor regulates the expression of Tim-3.T-cell based immunotherapy in experimental autoimmune encephalomyelitis and multiple sclerosis.Th17 cells: effector T cells with inflammatory properties.Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease The role of CXCL10 in the pathogenesis of experimental septic shock Major role of gamma delta T cells in the generation of IL-17+ uveitogenic T cells.The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early prognostic antibodies in multiple sclerosis.Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice.Th17 cells in autoimmune demyelinating disease.Th 17 cells interplay with Foxp3+ Tregs in regulation of inflammation and autoimmunity.Inflammatory skin disease in K5.hTGF-beta1 transgenic mice is not dependent on the IL-23/Th17 inflammatory pathway.Animal models of atopic dermatitis.Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation.Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses.The roles of IL-12 and IL-23 in CD8+ T cell-mediated immunity against Listeria monocytogenes: Insights from a DC vaccination model.Experimental autoimmune encephalomyelitis in the mouse.

P2860

Q24609737-A20E4C21-4E15-49B3-809A-4C9A013737FC Q24677051-A157414D-507F-4E53-8EFD-1DDF6439BB47 Q24679426-3816D0AA-6A77-46DC-BF71-E9274A9A5544 Q24681662-1F77EA88-47AB-4AEC-9BEF-89AAF56006A7 Q26770523-0A69B8DB-C520-4318-9413-AE4523BD4951 Q27009502-F6879EE6-52FC-437A-9F4D-6E566BA10F6C Q27687800-FEE98A46-E5CD-4C1C-B914-D5582C1F872D Q28086853-6EB1CDF2-C42D-4D70-AEDC-42BC5BF49FD6 Q28394921-B3F1E70F-F4C8-471C-9677-A80F95012B86 Q28513010-41F74AE2-EB31-4948-B1F3-4FA4AF32BB10 Q28533202-2D890903-3DE6-4419-A6B9-12D492F3CDBB Q30439547-E3DE3F7D-CEFE-4358-89EA-3ED61C52358B Q30486061-D1A56ED6-5DB3-435B-8D34-DA920D82FAD5 Q30620977-41F7FBEA-8A0D-4A6E-B82F-422178DDC677 Q30699740-F0C1364C-24D1-4BE2-A3DE-60ECC678CDEA Q31036486-905F0FCD-C606-47A2-9ABF-78791BA4734D Q33326648-A3E50F2C-8256-45B1-A82C-F8C1310A46DF Q33611073-993238AF-E1D8-4881-9E26-31E50E2DB82C Q33625887-980BB9D9-7580-4657-9A50-B2802FC59026 Q33636927-77E00AB3-9329-47E9-A17A-CD24D5952A30 Q33681689-0E4C6FC7-535E-4244-B729-F05FC1ECF5D2 Q33721890-22CCD84C-0D50-4C73-8EC5-269B0AC44662 Q33723154-F0A38267-947E-47BA-B594-F9F93C45FC98 Q33732092-04EC1756-0928-4C40-BBA2-94D78FFD2DE4 Q33753720-524D9047-D80D-4CF3-89FF-B57A13DD7924 Q33785953-1E5EFD99-D71A-4AF7-9160-1671077E770B Q33821851-71F7FC3B-2A91-46F7-A2B1-C07775E89108 Q33829024-E4635AAA-94B0-4DC6-B9C6-D94980F5C8D5 Q33833964-801BD3EB-F439-43AB-8C79-78CB9AE4C84C Q33834605-A2DA5135-E2FD-4B6A-9819-C76CD1760457 Q33835084-0D3DC34F-5F47-44F4-AE38-FA9A29D56924 Q33867796-7A3372E7-C4F4-4A06-8EB8-887FE1CD839F Q33894387-86EEA1BD-3088-4DA9-8ABD-AECF759AD563 Q33911969-DB4B208A-D5CD-4E2E-BC11-BCC345242E9A Q33915252-45BF60E5-0A80-4548-BDC6-1533A74FBD87 Q33923351-C9EA5C4F-4F36-40A8-A190-EDE38B9DA71A Q33927253-71062F4C-070B-4DBF-82B4-7B6B7F0D87E1 Q33944262-6ED772EA-973C-45E3-AB7B-782048FDB9C0 Q33987288-D1D8912B-3B15-4954-9942-050190646292 Q34041971-C78E775D-361E-4221-8DFC-510CAFE66347

P2860

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

http://www.wikidata.org/entity/Q34575334

description

2006 nî lūn-bûn

@nan

2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@ast

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@en

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@nl

type

label

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@ast

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@en

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@nl

prefLabel

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@ast

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@en

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@nl

P1433

Q34575334-3B8AE7B1-703B-4835-9C00-7F84D54CA89F

P1476

Q34575334-DA60A038-B619-42FA-9C1C-3057658B6355

P2093

Q34575334-329DACCA-8F7E-4773-9FDE-75D921A30C1A

Q34575334-39D76C7B-77DF-491E-A806-4FB91581D53F

Q34575334-454E6894-038B-4EC5-8EFE-C6CE9023CF8E

Q34575334-7DEADD15-C957-4AE9-A619-825C96465D8D

Q34575334-7E4929C2-4125-406C-B42A-2B1AA80AC919

Q34575334-8EFE2D7B-E9BC-4C26-9DE5-02A9A7DFD750

Q34575334-93E16559-CB4F-456A-BD79-C7B8C331249A

Q34575334-A8A3F744-952B-40D5-B37F-19D5772CA5B7

Q34575334-B53E8F1D-DC02-446A-A442-A15637B11D68

Q34575334-C4AE68AE-A073-4AFD-9E74-9C1DE06BA7ED

P2860

Q34575334-01933ACE-55A7-40E3-A540-DC9843EF78B8

Q34575334-01D50CFB-E44B-412C-B85F-E756B592462D

Q34575334-086C2715-4B1C-428A-8ED2-352AA46ECABD

Q34575334-0A5D6C73-A5E3-48FC-8C12-A8B3F2C67D72

Q34575334-0AD22577-9933-4B8F-8F98-85121990BBD1

Q34575334-18E04E7C-CF3D-4D3A-8477-6452AC8D1992

Q34575334-230D2BAE-D132-4128-9FCB-C417C167033F

Q34575334-2735BEFD-9706-4B0C-989B-7B36183766EF

Q34575334-3445DACD-3FE7-463B-8C6B-9359C7C49718

Q34575334-42D33884-25DA-4CD3-BDC7-1433568A5281

P304

Q34575334-C349C188-63D7-4043-AF23-86E46FD52937

P31

Q34575334-B7D3B7B2-8E02-41AB-9006-EEFE4B0D450F

P356

Q34575334-0258A580-7080-449E-934E-554F3E37BFE6

P407

Q34575334-71C31EC4-5640-464A-8F98-4AE32C7D8111

P433

Q34575334-FDE6DC86-CA6D-4F62-B938-2E8A342A2893

P478

Q34575334-6D1D7D7F-A5E0-4280-8EA2-BC7449A5AEE4

P577

Q34575334-5DD48BDB-1561-40AE-BB78-FEFEED7189BF

P5875

Q34575334-8DDA33D3-D766-4217-9B2D-18427C5CB7FC

P698

Q34575334-66E26F56-EEDD-4D30-AA80-8FC226A96837

P932

Q34575334-77515163-79B2-47C6-8574-7C9663848149

P356

P1433

Journal of Clinical Investigation

P1476

Anti-IL-23 therapy inhibits mu ...... s autoimmune encephalomyelitis

@en

P2093

Barbara Joyce-Shaikh

http://www.w3.org/2001/XMLSchema#string

Brent McKenzie

http://www.w3.org/2001/XMLSchema#string

Christopher A Hunter

http://www.w3.org/2001/XMLSchema#string

Claire L Langrish

http://www.w3.org/2001/XMLSchema#string

Daniel J Cua

http://www.w3.org/2001/XMLSchema#string

Jason S Stumhofer

http://www.w3.org/2001/XMLSchema#string

Justin Low

http://www.w3.org/2001/XMLSchema#string

Leonard Presta

http://www.w3.org/2001/XMLSchema#string

Robert A Kastelein

http://www.w3.org/2001/XMLSchema#string

Tatyana Churakovsa

http://www.w3.org/2001/XMLSchema#string

P2860

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

Anti-interleukin-12 antibody for active Crohn's disease

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17.

Immunopathogenesis of multiple sclerosis: the role of T cells.

P304

1317-1326

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI25308

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

116

http://www.w3.org/2001/XMLSchema#string

P577

2006-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7109391

http://www.w3.org/2001/XMLSchema#string

P698

16670771

http://www.w3.org/2001/XMLSchema#string

P932

1450386

http://www.w3.org/2001/XMLSchema#string