A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
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CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMDBlue-light filtering intraocular lenses (IOLs) for protecting macular healthAge-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNAGenome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypesA variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degenerationGenetics and age-related macular degeneration: a practical review for the clinicianManagement of neovascular age-related macular degeneration: current state-of-the-art care for optimizing visual outcomes and therapies in developmentThe proteomics of drusenStructural and functional analysis of the PDZ domains of human HtrA1 and HtrA3Molecular Adaptation of the DegQ Protease to Exert Protein Quality Control in the Bacterial Cell EnvelopeGenetic determinants of age-related macular degeneration in diverse populations from the PAGE studyProtoporphyrins enhance oligomerization and enzymatic activity of HtrA1 serine proteaseA mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is highly expressed in retina that exhibits a large area of intrinsic disorderToward an integrated software platform for systems pharmacologyOverexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch's membrane via cleavage of extracellular matrix componentsGenetic association studies in nursing practice and scholarshipGenetic factors in nonsmokers with age-related macular degeneration revealed through genome-wide gene-environment interaction analysisHeritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypesHomocysteine and risk of age-related macular degeneration: a systematic review and meta-analysis.Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular diseaseLOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: A HuGE review and meta-analysisGenetic markers and biomarkers for age-related macular degeneration.Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking.Extreme retinal remodeling triggered by light damage: implications for age related macular degeneration.C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes.The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degenerationAnalysis of the indel at the ARMS2 3'UTR in age-related macular degeneration.Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data.CTGF is increased in basal deposits and regulates matrix production through the ERK (p42/p44mapk) MAPK and the p38 MAPK signaling pathways.Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration.Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables.Identification of tubulins as substrates of serine protease HtrA1 by mixture-based oriented peptide library screening.Epistatic module detection for case-control studies: a Bayesian model with a Gibbs sampling strategy.Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approachGenetic and functional dissection of HTRA1 and LOC387715 in age-related macular degenerationAnimals as models of age-related macular degeneration: an imperfect measure of the truth.Liver and adipose expression associated SNPs are enriched for association to type 2 diabetesAn association study of SERPING1 gene and age-related macular degeneration in a Han Chinese populationPositive association of common variants in CD36 with neovascular age-related macular degeneration
P2860
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P2860
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@ast
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@en
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@nl
type
label
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@ast
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@en
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@nl
prefLabel
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@ast
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@en
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@nl
P2093
P356
P1433
P1476
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.
@en
P2093
Andrew Dewan
D Joshua Cameron
Daniel Gibbs
Erik Pearson
Jennifer Harmon
Josephine Hoh
Kang Zhang
Kimberly Howes
Nicola J Camp
P304
P356
10.1126/SCIENCE.1133811
P407
P577
2006-10-19T00:00:00Z