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Stress signalling pathways that impair prefrontal cortex structure and functionMultidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferationNovel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012Genetically-encoded tools for cAMP probing and modulation in living systemsSmall G proteins in the cardiovascular system: physiological and pathological aspectsProtein kinase A activity and anchoring are required for ovarian cancer cell migration and invasionRole of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cellsMitochondrial cAMP signalingThe role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECsCan the anti-inflammatory activities of β2-agonists be harnessed in the clinical setting?Metabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathwayEpac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migrationDifferential distribution of exchange proteins directly activated by cyclic AMP within the adult rat retinaNerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to EpacExchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channelsDownregulation of Rap1GAP contributes to Ras transformationEpac2 induces synapse remodeling and depression and its disease-associated forms alter spinesActivation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cellsAngiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptationRecent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Epac signaling is required for hippocampus-dependent memory retrieval.Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia.Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cellsIloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury.Divergent label-free cell phenotypic pharmacology of ligands at the overexpressed β₂-adrenergic receptors.Cyclic AMP accelerates calcium waves in pancreatic acinar cellsActivation of focal adhesion kinase and JNK contributes to the extracellular matrix and cAMP-GEF mediated survival from bile acid induced apoptosis in rat hepatocytesEpac, not PKA catalytic subunit, is required for 3T3-L1 preadipocyte differentiation.PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes.Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion.Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling.Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.Epac is required for GLP-1R-mediated inhibition of oxidative stress and apoptosis in cardiomyocytesProstaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotectionAn evolutionary analysis of cAMP-specific Phosphodiesterase 4 alternative splicing.PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.Prostaglandin E2 reverses aberrant production of an inflammatory chemokine by microglia from Sandhoff disease model mice through the cAMP-PKA pathwaybeta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation.AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysisACTH induces Cav3.2 current and mRNA by cAMP-dependent and cAMP-independent mechanisms.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Epac proteins: multi-purpose cAMP targets.
@ast
Epac proteins: multi-purpose cAMP targets.
@en
Epac proteins: multi-purpose cAMP targets.
@nl
type
label
Epac proteins: multi-purpose cAMP targets.
@ast
Epac proteins: multi-purpose cAMP targets.
@en
Epac proteins: multi-purpose cAMP targets.
@nl
prefLabel
Epac proteins: multi-purpose cAMP targets.
@ast
Epac proteins: multi-purpose cAMP targets.
@en
Epac proteins: multi-purpose cAMP targets.
@nl
P1476
Epac proteins: multi-purpose cAMP targets.
@en
P2093
Johannes L Bos
P304
P356
10.1016/J.TIBS.2006.10.002
P577
2006-11-02T00:00:00Z