Rapid optimization and prototyping for therapeutic antibody-like molecules.
about
Advances in Antibody DesignCDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery.The structure of dual-variable-domain immunoglobulin molecules alone and bound to antigenDevelopment trends for generation of single-chain antibody fragments.A critical role for HER3 in HER2-amplified and non-amplified breast cancers: function of a kinase-dead RTK.Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies.Comprehensive optimization of a single-chain variable domain antibody fragment as a targeting ligand for a cytotoxic nanoparticle.A dual-targeting triplebody mediates preferential redirected lysis of antigen double-positive over single-positive leukemic cells.Engineering multivalent antibodies to target heregulin-induced HER3 signaling in breast cancer cellsHER3/ErbB3, an emerging cancer therapeutic target.A novel screening method to assess developability of antibody-like molecules.Targeting HER3 using mono- and bispecific antibodies or alternative scaffolds.Dual-targeting triplebody 33-3-19 mediates selective lysis of biphenotypic CD19+ CD33+ leukemia cells.Improving the developability of an anti-EphA2 single-chain variable fragment for nanoparticle targeting.
P2860
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P2860
Rapid optimization and prototyping for therapeutic antibody-like molecules.
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@ast
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@en
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@nl
type
label
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@ast
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@en
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@nl
prefLabel
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@ast
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@en
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@nl
P2093
P2860
P356
P1476
Rapid optimization and prototyping for therapeutic antibody-like molecules.
@en
P2093
Alexey A Lugovskoy
Birgit Schoeberl
Bryan Johnson
Jason Baum
Jonathan Fitzgerald
Kathy Zhang
Maja Razlog
Neeraj Kohli
P2860
P304
P356
10.4161/MABS.23363
P577
2013-02-07T00:00:00Z