Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. - Wikidata - wikimedia - TriplyDB

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.

http://www.wikidata.org/entity/Q34580828

about

The PICALM protein plays a key role in iron homeostasis and cell proliferation Expression of a CALM-AF10 fusion gene leads to Hoxa cluster overexpression and acute leukemia in transgenic mice Zebrafish as a model for cancer self-renewal NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.Murine models of acute leukemia: important tools in current pediatric leukemia research.Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.MicroRNA-34a perturbs B lymphocyte development by repressing the forkhead box transcription factor Foxp1.The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells.Tackling the cancer stem cells - what challenges do they pose?Suppression of leukemia development caused by PTEN loss.Effects of iron depletion on CALM-AF10 leukemias.Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models.STAT activation status differentiates leukemogenic from non-leukemogenic stem cells in AML and is suppressed by arsenic in t(6;9)-positive AML Right on target: eradicating leukemic stem cells.Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene.Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers.FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia.Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model Leukemia stem cells in a genetically defined murine model of blast-crisis CML.Context Matters: Distinct Disease Outcomes as a Result of Crebbp Hemizygosity in Different Mouse Bone Marrow Compartments The evolving concept of cancer and metastasis stem cells Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells.CREB is a critical regulator of normal hematopoiesis and leukemogenesis.The role of CALM-AF10 gene fusion in acute leukemia.A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis.HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.CATS (FAM64A) abnormal expression reduces clonogenicity of hematopoietic cells.The cancer stem cell: premises, promises and challenges.The beating heart of melanomas: a minor subset of cancer cells sustains tumor growth.The hematopoietic stem cell niche--home for friend and foe?Role of Hippo signaling in cancer stem cells.Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice.The clathrin-binding domain of CALM-AF10 alters the phenotype of myeloid neoplasms in mice.Decoupling of tumor-initiating activity from stable immunophenotype in HoxA9-Meis1-driven AML.Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice.

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Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia.

http://www.wikidata.org/entity/Q34580828

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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name

Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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J.CCR.2006.08.023

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Acute myeloid leukemia is prop ...... f CALM/AF10-positive leukemia.

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Alexandre Krause

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Aniruddha J Deshpande

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Christian Buske

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Christiane Pott

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Cristina Mecucci

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Elizabeth Macintyre

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Florian Kuchenbauer

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Hendrik Reuter

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Meinhard Hahn

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Michael Kneba

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363-374

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scholarly article

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10.1016/J.CCR.2006.08.023

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5

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10

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R Keith Humphries

Leticia Quintanilla-Martinez

Stefan K. Bohlander

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2006-11-01T00:00:00Z

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6699035

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17097559

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