Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. - Wikidata - wikimedia - TriplyDB

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.

http://www.wikidata.org/entity/Q34582788

about

Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropylphosphonic acid epoxidase using 17O-enriched substrates and substrate analogues Fosfomycin: A First-Line Oral Therapy for Acute Uncomplicated Cystitis Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways Crystal Structure of Fosfomycin Resistance Kinase FomA from Streptomyces wedmorensis Characterization and structure of DhpI, a phosphonateO-methyltransferase involved in dehydrophos biosynthesis Structural and Biochemical Insights into the Mechanism of Fosfomycin Phosphorylation by Fosfomycin Resistance Kinase FomA Amidoligases with ATP-grasp, glutamine synthetase-like and acetyltransferase-like domains: synthesis of novel metabolites and peptide modifications of proteins Molecular cloning and heterologous expression of the dehydrophos biosynthetic gene cluster Deciphering the late biosynthetic steps of antimalarial compound FR-900098.Biosynthesis of rhizocticins, antifungal phosphonate oligopeptides produced by Bacillus subtilis ATCC6633 Manipulating natural product biosynthetic pathways via DNA assembler.Cloning and heterologous expression of the spectinabilin biosynthetic gene cluster from Streptomyces spectabilis.Cyanohydrin phosphonate natural product from Streptomyces regensis.Stereochemistry of Hydride Transfer by Group III Alcohol Dehydrogenases Involved in Phosphonate Biosynthesis Structure and mechanism of enzymes involved in biosynthesis and breakdown of the phosphonates fosfomycin, dehydrophos, and phosphinothricin.Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide.Rapid characterization and engineering of natural product biosynthetic pathways via DNA assembler DNA assembler: a synthetic biology tool for characterizing and engineering natural product gene clusters.Refactoring the silent spectinabilin gene cluster using a plug-and-play scaffold.Integrative conjugative elements of the ICEPan family play a potential role in Pantoea ananatis ecological diversification and antibiosis High-efficiency multiplex genome editing of Streptomyces species using an engineered CRISPR/Cas system.Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes.Different biosynthetic pathways to fosfomycin in Pseudomonas syringae and Streptomyces species.Diversity and Evolutionary Analysis of Iron-Containing (Type-III) Alcohol Dehydrogenases in Eukaryotes Identification of ACE pharmacophore in the phosphonopeptide metabolite K-26.Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways.Biosynthesis of phosphonic and phosphinic acid natural products.Diversity and abundance of phosphonate biosynthetic genes in nature Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster.Systems metabolic engineering: genome-scale models and beyond.Prospecting for new bacterial metabolites: a glossary of approaches for inducing, activating and upregulating the biosynthesis of bacterial cryptic or silent natural products.Phenolic polyketides from the co-cultivation of marine-derived Penicillium sp. WC-29-5 and Streptomyces fradiae 007.Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis.The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.Enhanced Solubilization of Class B Radical S-adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli.TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases.A (Re)Discovery of the Fom3 Substrate.-PcxL and HpxL are flavin-dependent, oxime-forming N-oxidases in phosphonocystoximic acid biosynthesis in Streptomyces.

P2860

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P2860

Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.

http://www.wikidata.org/entity/Q34582788

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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J.CHEMBIOL.2006.09.007

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Chemistry and Biology

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Heterologous production of fos ...... mal biosynthetic gene cluster.

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Huimin Zhao

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Joshua A V Blodgett

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Neil L Kelleher

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Paul M Thomas

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Ryan D Woodyer

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Wilfred A van der Donk

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William W Metcalf

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Zengyi Shao

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10.1016/J.CHEMBIOL.2006.09.007

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