An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.
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A unified model of the GABA(A) receptor comprising agonist and benzodiazepine binding sitesDiazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligandsA Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor ModelAllosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected].Selective targeting of the α5-subunit of GABAA receptors relaxes airway smooth muscle and inhibits cellular calcium handlingSmall molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.Design, synthesis, and subtype selectivity of 3,6-disubstituted β-carbolines at Bz/GABA(A)ergic receptors. SAR and studies directed toward agents for treatment of alcohol abuse.Flavonoid modulation of GABA(A) receptors.First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development.Search for α3β₂/₃γ2 subtype selective ligands that are stable on human liver microsomesDesign, Synthesis and Anticonvulsant Activity of 2-(2-Phenoxy) phenyl- 1,3,4-oxadiazole DerivativesAn Improved Process for the Synthesis of 4H-Imidazo[1,5-a][1,4]benzodiazepines.Insights into the structure and pharmacology of GABA(A) receptors.3-fluoro-GABA enantiomers: exploring the conformation of GABA binding to GABAA receptors and GABA aminotransferase.Pharmacophore models for GABA(A) modulators: implications in CNS drug discovery.Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors.Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are differentSynthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability, Pharmacokinetics, and Anxiolytic EfficacyComparison of the relative propensities of isoamyl nitrite and sodium nitrite to ameliorate acute cyanide poisoning in mice and a novel antidotal effect arising from anesthetics.A two step synthesis of BzR/GABAergic active flavones via a Wacker-related oxidation.Development of a two-step route to 3-PBC and βCCt, two agents active against alcohol self-administration in rodent and primate models.Deciphering the binding mode of Zolpidem to GABA(A) α₁ receptor - insights from molecular dynamics simulation.Effects of the benzodiazepine GABAA α1-preferring antagonist 3-isopropoxy-β-carboline hydrochloride (3-ISOPBC) on alcohol seeking and self-administration in baboons.
P2860
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P2860
An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
An updated unified pharmacopho ...... ite on gamma-aminobutyric acid
@nl
An updated unified pharmacopho ...... ation with comparative models.
@ast
An updated unified pharmacopho ...... ation with comparative models.
@en
type
label
An updated unified pharmacopho ...... ite on gamma-aminobutyric acid
@nl
An updated unified pharmacopho ...... ation with comparative models.
@ast
An updated unified pharmacopho ...... ation with comparative models.
@en
altLabel
An Updated Unified Pharmacopho ...... lation with Comparative Models
@en
prefLabel
An updated unified pharmacopho ...... ite on gamma-aminobutyric acid
@nl
An updated unified pharmacopho ...... ation with comparative models.
@ast
An updated unified pharmacopho ...... ation with comparative models.
@en
P2093
P50
P1476
An updated unified pharmacopho ...... ation with comparative models.
@en
P2093
B A Cromer
C C Kaczorowski
C J Morton
F J Helmstetter
M W Parker
R Furtmüller
P304
P356
10.2174/092986707782360097
P577
2007-01-01T00:00:00Z