PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc. - Wikidata - wikimedia - TriplyDB

PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.

PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.

http://www.wikidata.org/entity/Q34589291

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FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma MicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cells Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes Variations in gene and protein expression in canine chondrodystrophic nucleus pulposus cells following long-term three-dimensional culture.Ex vivo observation of human nucleus pulposus chondrocytes isolated from degenerated intervertebral discs MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects Endothelial cells direct human mesenchymal stem cells for osteo- and chondro-lineage differentiation through endothelin-1 and AKT signaling.Prenatal ethanol exposure increases osteoarthritis susceptibility in female rat offspring by programming a low-functioning IGF-1 signaling pathway.Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation Rapamycin-Induced Hypoxia Inducible Factor 2A Is Essential for Chondrogenic Differentiation of Amniotic Fluid Stem Cells Hypoxia enhances chondrogenesis and prevents terminal differentiation through PI3K/Akt/FoxO dependent anti-apoptotic effect.SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway.Cell signaling pathways related to pain receptors in the degenerated disk.IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells.Molecular regulation of CCN2 in the intervertebral disc: lessons learned from other connective tissues Orexin Plays a Role in Growth Impediment Induced by Obstructive Sleep Breathing in Rats.The roles and perspectives of microRNAs as biomarkers for intervertebral disc degeneration.Exogenous and autocrine growth factors stimulate human intervertebral disc cell proliferation via the ERK and Akt pathways.The role of angiopoietin-2 in nucleus pulposus cells during human intervertebral disc degeneration.The PI3K/Akt pathway: a critical player in intervertebral disc degeneration.RETRACTED: Gene expression analysis in response to osmotic stimuli in the intervertebral disc with DNA microarray.Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro.Clinical implication of Sox9 and activated Akt expression in pancreatic ductal adenocarcinoma.Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway.RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE?Hypoxia suppresses serum deprivation-induced degradation of the nucleus pulposus cell extracellular matrix through the JNK and NF-κB pathways.PI3Kγ promotes vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis via a SOX9-dependent mechanism

P2860

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P2860

PI3K/AKT regulates aggrecan gene expression by modulating Sox9 expression and activity in nucleus pulposus cells of the intervertebral disc.

http://www.wikidata.org/entity/Q34589291

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

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Journal of Cellular Physiology

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PI3K/AKT regulates aggrecan ge ...... ls of the intervertebral disc.

@en

P2093

Akihiko Hiyama

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Chin-Chang Cheng

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Irving M Shapiro

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Makarand V Risbud

http://www.w3.org/2001/XMLSchema#string

Sachin Gajghate

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Yoshiyasu Uchiyama

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P2860

Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer

A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

The phosphoinositide 3-kinase pathway

Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300

Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth.

The PTEN-PI3K pathway: of feedbacks and cross-talks.

Myogenic signaling of phosphatidylinositol 3-kinase requires the serine-threonine kinase Akt/protein kinase B.

Diffusion of small solutes into the intervertebral disc: as in vivo study.

P304

668-676

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scholarly article

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10.1002/JCP.21904

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3

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221

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2009-12-01T00:00:00Z

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26771289

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19711351

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3042319

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