Mechanism of free-radical generation by nitric oxide synthase.
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Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine DerivativesStructure-Guided Design of Selective Inhibitors of Neuronal Nitric Oxide SynthaseSelective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics SimulationsPotent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of MelanomaSimplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase InhibitionPotential implication of the chemical properties and bioactivity of nitrone spin traps for therapeuticsIntraprotein electron transfer in inducible nitric oxide synthase holoenzymeRegulation of interdomain electron transfer in the NOS output state for NO productionPotent and selective neuronal nitric oxide synthase inhibitors with improved cellular permeability.The bioinorganic chemistry of iron in oxygenases and supramolecular assemblies.Reactive nitrogen species reactivities with nitrones: theoretical and experimental studies.Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.How to control NO production in cells: N(omega),N(omega)-dimethyl-L-arginine dimethylaminohydrolase as a novel drug target.Analytical chemistry of nitric oxide.Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.Recent advances toward improving the bioavailability of neuronal nitric oxide synthase inhibitors.Ruthenium-nitrosyl complexes with glycine, L-alanine, L-valine, L-proline, D-proline, L-serine, L-threonine, and L-tyrosine: synthesis, X-ray diffraction structures, spectroscopic and electrochemical properties, and antiproliferative activity.Ruthenium nitrosyls derived from tetradentate ligands containing carboxamido-N and phenolato-o donors: syntheses, structures, photolability, and time dependent density functional theory studiesLessons on O2 and NO bonding to heme from ab initio multireference/multiconfiguration and DFT calculations.Syntheses, structures, and photochemistry of manganese nitrosyls derived from designed Schiff base ligands: potential NO donors that can be activated by near-infrared light.Interactions between substrates and the haem-bound nitric oxide of ferric and ferrous bacterial nitric oxide synthases.Kinetics of CO Recombination to the Heme in Geobacillus Stearothermophilus Nitric Oxide Synthase.NO synthase isoforms specifically modify peroxynitrite reactivity.Calmodulin activates electron transfer through neuronal nitric-oxide synthase reductase domain by releasing an NADPH-dependent conformational lock.Thermodynamic and kinetic analysis of the nitrosyl, carbonyl, and dioxy heme complexes of neuronal nitric-oxide synthase. The roles of substrate and tetrahydrobiopterin in oxygen activation.Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.A novel copper(II) complex as a nitric oxide turn-on fluorosensor: intracellular applications and DFT calculation.Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.Activation of peroxynitrite by inducible nitric-oxide synthase: a direct source of nitrative stress.The Preparation, Structural Characteristics, and Physical Chemical Properties of Metal-Nitrosyl Complexes.Oxygen metabolism by neuronal nitric-oxide synthase.Oxygen metabolism by endothelial nitric-oxide synthaseOsmium-Nitrosyl Complexes with Glycine, Picolinic Acid, L-Proline andD-Proline: Synthesis, Structures and Antiproliferative ActivityImportance of Val567 on heme environment and substrate recognition of neuronal nitric oxide synthase
P2860
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P2860
Mechanism of free-radical generation by nitric oxide synthase.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Mechanism of free-radical generation by nitric oxide synthase.
@ast
Mechanism of free-radical generation by nitric oxide synthase.
@en
Mechanism of free-radical generation by nitric oxide synthase.
@nl
type
label
Mechanism of free-radical generation by nitric oxide synthase.
@ast
Mechanism of free-radical generation by nitric oxide synthase.
@en
Mechanism of free-radical generation by nitric oxide synthase.
@nl
prefLabel
Mechanism of free-radical generation by nitric oxide synthase.
@ast
Mechanism of free-radical generation by nitric oxide synthase.
@en
Mechanism of free-radical generation by nitric oxide synthase.
@nl
P2093
P356
P1433
P1476
Mechanism of free-radical generation by nitric oxide synthase.
@en
P2093
Gerald M Rosen
Sovitj Pou
P304
P356
10.1021/CR010187S
P577
2002-04-01T00:00:00Z