about
Rac and Rho GTPases in cancer cell motility controlRhoA: a therapeutic target for chronic myeloid leukemiaDLC-1, a Rho GTPase-activating protein with tumor suppressor function, is essential for embryonic developmentRACK1 promotes breast carcinoma migration/metastasis via activation of the RhoA/Rho kinase pathwayDifferential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatmentRational design of small molecule inhibitors targeting RhoA subfamily Rho GTPasesMatrix metalloproteinase induction of Rac1b, a key effector of lung cancer progressionThe DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activationGTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoScambio, a novel guanine nucleotide exchange factor for RhoRho GTPase regulation by miRNAs and covalent modificationsCooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activityStructural basis for the signaling specificity of RhoG and Rac1 GTPasesIsolation of a novel member of small G protein superfamily and its expression in colon cancerDLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinomaIdentification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoformIdentification of potential small molecule binding pockets on Rho family GTPasesP190A RhoGAP is required for mammary gland developmentEvolutionary genomics of human intellectual disabilitySmall molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasisInnate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in GambiansSanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation.Epithelial cell transforming sequence 2 in human oral cancer.Isoprenoids, small GTPases and Alzheimer's disease.Effects of the tumor inhibitory triterpenoid avicin G on cell integrity, cytokinesis, and protein ubiquitination in fission yeast.Simultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters.The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.Alteration of proteomic profiles in PBMC isolated from patients with Fabry disease: preliminary findings.CNF1-induced ubiquitylation and proteasome destruction of activated RhoA is impaired in Smurf1-/- cellsNovel split-luciferase-based genetically encoded biosensors for noninvasive visualization of Rho GTPases.RhoGTPases and p53 are involved in the morphological appearance and interferon-alpha response of hairy cellsInvolvement of Rho family GTPases in p19Arf- and p53-mediated proliferation of primary mouse embryonic fibroblasts.Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13Increased p190RhoGEF expression in activated B cells correlates with the induction of the plasma cell differentiation.Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells.A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cellsRole of chimaerins, a group of Rac-specific GTPase activating proteins, in T-cell receptor signaling.1-42 β-amyloid peptide requires PDK1/nPKC/Rac 1 pathway to induce neuronal death.ARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells.
P2860
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P2860
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The role of Rho GTPases in disease development.
@ast
The role of Rho GTPases in disease development.
@en
The role of Rho GTPases in disease development.
@nl
type
label
The role of Rho GTPases in disease development.
@ast
The role of Rho GTPases in disease development.
@en
The role of Rho GTPases in disease development.
@nl
prefLabel
The role of Rho GTPases in disease development.
@ast
The role of Rho GTPases in disease development.
@en
The role of Rho GTPases in disease development.
@nl
P1433
P1476
The role of Rho GTPases in disease development.
@en
P2093
Benjamin Boettner
Linda Van Aelst
P304
P356
10.1016/S0378-1119(02)00426-2
P407
P577
2002-03-01T00:00:00Z