A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells - Wikidata - wikimedia - TriplyDB

A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

http://www.wikidata.org/entity/Q36357411

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Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture Deletion of epidermal Rac1 inhibits HPV-8 induced skin papilloma formation and facilitates HPV-8- and UV-light induced skin carcinogenesis Site-dependent E-cadherin cleavage and nuclear translocation in a metastatic colorectal cancer model.Cancer stem cells and cisplatin-resistant cells isolated from non-small-lung cancer cell lines constitute related cell populations.Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion.ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis.The diverse roles of Rac signaling in tumorigenesis Rho GTPase signaling in the development of colorectal cancer.Rho GTPases modulate malignant transformation of tumor cells.PLAGL2 regulates actin cytoskeletal architecture and cell migration.Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction.The small GTPase Rac1 is involved in the maintenance of stemness and malignancies in glioma stem-like cells.DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer.PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1.Rac1 is required for oncolytic NDV replication in human cancer cells and establishes a link between tumorigenesis and sensitivity to oncolytic virus.Discovery and characterization of small molecule Rac1 inhibitors shRNA-induced silencing of Ras-related C3 botulinum toxin substrate 1 inhibits the proliferation of colon cancer cells through upregulation of BAD and downregulation of cyclin D1.

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A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

http://www.wikidata.org/entity/Q36357411

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

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A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

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type

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A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

@ast

A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

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prefLabel

A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

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A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

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AJPATH.2008.070561

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The American Journal of Pathology

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A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells

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Alicia Boluda

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Carolina Espina

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Lourdes García Oroz

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Manuel Nistal

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María Teresa Gómez del Pulgar

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María Virtudes Céspedes

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Miguel Angel García-Cabezas

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Paloma Cejas

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P2860

The Hallmarks of Cancer

Asef, a link between the tumor suppressor APC and G-protein signaling

Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Global cancer statistics, 2002

A genetic model for colorectal tumorigenesis

Wnt signaling and cancer

A system for stable expression of short interfering RNAs in mammalian cells

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Rho GTPases in cell biology

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10.2353/AJPATH.2008.070561

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1

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Salvador Aznar Benitah

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