Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model - Wikidata - wikimedia - TriplyDB

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

http://www.wikidata.org/entity/Q34596280

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The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors The kinase domain of mitochondrial PINK1 faces the cytoplasm The ER stress factor XBP1s prevents amyloid-beta neurotoxicity Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration Golgi Fragmentation in ALS Motor Neurons. New Mechanisms Targeting Microtubules, Tethers, and Transport Vesicles Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases Molecular motor proteins and amyotrophic lateral sclerosis An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans The complex molecular biology of amyotrophic lateral sclerosis (ALS)Protein disulphide isomerase protects against protein aggregation and is S-nitrosylated in amyotrophic lateral sclerosis Seipinopathy: a novel endoplasmic reticulum stress-associated disease The critical role of membralin in postnatal motor neuron survival and disease Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.Palmitoylation of superoxide dismutase 1 (SOD1) is increased for familial amyotrophic lateral sclerosis-linked SOD1 mutants Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice Characterization of detergent-insoluble proteins in ALS indicates a causal link between nitrative stress and aggregation in pathogenesis.Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function An in vitro model for Lewy body-like hyaline inclusion/astrocytic hyaline inclusion: induction by ER stress with an ALS-linked SOD1 mutation Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.Three common GJB2 mutations causing nonsyndromic hearing loss in Chinese populations are retained in the endoplasmic reticulum.Perturbation of endoplasmic reticulum homeostasis facilitates prion replication.SOD1, an unexpected novel target for cancer therapy Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis.Mitochondrial dysfunction and intracellular calcium dysregulation in ALS Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis.Compensatory Motor Neuron Response to Chromatolysis in the Murine hSOD1(G93A) Model of Amyotrophic Lateral Sclerosis The unfolded protein response in familial amyotrophic lateral sclerosis.Activation of interferon signaling pathways in spinal cord astrocytes from an ALS mouse model.Dysfunction of endocytic kinase AAK1 in ALS The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice.Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines Activation of the endoplasmic reticulum stress response in skeletal muscle of G93A*SOD1 amyotrophic lateral sclerosis mice.In vivo pathogenic role of mutant SOD1 localized in the mitochondrial intermembrane space Overexpression of CCS in G93A-SOD1 mice leads to accelerated neurological deficits with severe mitochondrial pathology.Guanabenz Treatment Accelerates Disease in a Mutant SOD1 Mouse Model of ALS.

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Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model

http://www.wikidata.org/entity/Q34596280

description

2006 nî lūn-bûn

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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Proceedings of the National Academy of Sciences of the United States of America

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Spinal cord endoplasmic reticu ...... de dismutase-1 in an ALS model

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Alexander A Sosunov

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Christelle Guégan

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Gabriele Almer

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Guy M McKhann

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Hitoshi Kikuchi

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Makiko Nagai

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Satoshi Yamashita

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Zuoshang Xu

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P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane.

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

The mammalian unfolded protein response

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6025-6030

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10.1073/PNAS.0509227103

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15

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103

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Serge Przedborski

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7183503

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16595634

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amyotrophic lateral sclerosis

Heat shock protein 5

Cyclic AMP-dependent transcription factor ATF-6 beta

endoplasmic reticulum

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1458691

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