Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
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MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine responseComparative review of Francisella tularensis and Francisella novicidaMicroarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversionFine tuning inflammation at the front door: macrophage complement receptor 3-mediates phagocytosis and immune suppression for Francisella tularensisTLR-dependent control of Francisella tularensis infection and host inflammatory responsesThe AIM2 inflammasome is critical for innate immunity to Francisella tularensisMonophosphoryl Lipid A Enhances Efficacy of a Francisella tularensis LVS-Catanionic Nanoparticle Subunit Vaccine against F. tularensis Schu S4 Challenge by Augmenting both Humoral and Cellular Immunity.Novel catanionic surfactant vesicle vaccines protect against Francisella tularensis LVS and confer significant partial protection against F. tularensis Schu S4 strainRole of TLR signaling in Francisella tularensis-LPS-induced, antibody-mediated protection against Francisella tularensis challenge.Identification of an essential Francisella tularensis subsp. tularensis virulence factor.Adaptation of Francisella tularensis to the mammalian environment is governed by cues which can be mimicked in vitro.Cytokine response in Balb/c mice infected with Francisella tularensis LVS and the Pohang isolatePhagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.GroEL and lipopolysaccharide from Francisella tularensis live vaccine strain synergistically activate human macrophagesRole of Toll-like receptors in host responses to a virulence antigen of Streptococcus mutans expressed by a recombinant, attenuated Salmonella vector vaccine.TLR2 Signaling is Required for the Innate, but Not Adaptive Response to LVS clpBA Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacyWhole-genome microarray analysis and functional characterization reveal distinct gene expression profiles and patterns in two mouse models of ileal inflammation.A mucosal subunit vaccine protects against lethal respiratory infection with Francisella tularensis LVS.Glycogen synthase kinase-3beta (GSK3beta) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in miceIKKβ in myeloid cells controls the host response to lethal and sublethal Francisella tularensis LVS infection.Discordant results obtained with Francisella tularensis during in vitro and in vivo immunological studies are attributable to compromised bacterial structural integrity.Innate immune recognition of francisella tularensis: activation of type-I interferons and the inflammasomeTLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.Role of mTOR downstream effector signaling molecules in Francisella tularensis internalization by murine macrophages.Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cellsTLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-kappaB.Francisella tularensis LVS-induced Interleukin-12 p40 cytokine production mediates dendritic cell migration through IL-12 Receptor β1.Production of anti-LPS IgM by B1a B cells depends on IL-1β and is protective against lung infection with Francisella tularensis LVSRevisiting the Gram-negative lipoprotein paradigm.Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domainInflammasome priming is similar for francisella species that differentially induce inflammasome activation.Role of primary human alveolar epithelial cells in host defense against Francisella tularensis infection.Toll-like receptor 2-mediated signaling requirements for Francisella tularensis live vaccine strain infection of murine macrophagesTranscriptome analysis of human immune responses following live vaccine strain (LVS) Francisella tularensis vaccinationToll-like receptor 2 controls the gamma interferon response to Francisella tularensis by mouse liver lymphocytes.Sensing gram-negative bacterial lipopolysaccharides: a human disease determinant?Toll-like receptors and leishmaniasis.Kdo hydrolase is required for Francisella tularensis virulence and evasion of TLR2-mediated innate immunity.Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4.
P2860
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P2860
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
description
2006 nî lūn-bûn
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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@ast
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@en
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@nl
type
label
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@ast
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@en
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@nl
prefLabel
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@ast
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@en
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@nl
P2093
P2860
P1476
Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS
@en
P2093
Jannet Katz
Michael Martin
Ping Zhang
Stefanie N Vogel
Suzanne M Michalek
P2860
P304
P356
10.1128/IAI.74.5.2809-2816.2006
P407
P577
2006-05-01T00:00:00Z