Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis
about
Regulation of Bim in Health and DiseaseMicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and developmentMicroRNAs as tools to predict glucocorticoid response in inflammatory bowel diseasesMechanism of T cell regulation by microRNAsmicroRNA Therapeutics in Cancer - An Emerging ConceptMicroRNA and transcription factor co-regulatory network analysis reveals miR-19 inhibits CYLD in T-cell acute lymphoblastic leukemiaExpression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenograftsThe metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 clusterDeep sequencing identification of novel glucocorticoid-responsive miRNAs in apoptotic primary lymphocytesTranslational profiling in childhood acute lymphoblastic leukemia: no evidence for glucocorticoid regulation of mRNA translation.Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3Increased expression of the pro-apoptotic protein BIM, a mechanism for cAMP/protein kinase A (PKA)-induced apoptosis of immature T cells.Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes.BH3-only proteins in apoptosis at a glanceThe BCL-2 protein family, BH3-mimetics and cancer therapy.Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk.MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesGlucocorticoids transcriptionally regulate miR-27b expression promoting body fat accumulation via suppressing the browning of white adipose tissueGlucocorticoids suppress T cell function by up-regulating microRNA-98MicroRNA-100/99a, deregulated in acute lymphoblastic leukaemia, suppress proliferation and promote apoptosis by regulating the FKBP51 and IGF1R/mTOR signalling pathwaysThe regulation of the mitochondrial apoptotic pathway by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cellsTargeting miR-375 in gastric cancer.Apoptosis and microRNA aberrations in cancer.Oncogenic and tumor suppressive roles of microRNAs in apoptosis and autophagy.The effects of microRNAs on glucocorticoid responsiveness.miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis.Glucocorticoid-mediated co-regulation of RCAN1-1, E4BP4 and BIM in human leukemia cells susceptible to apoptosis.Mitochondrial determinants of cancer health disparities.Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells.Involvement of miR17 pathway in glucocorticoid-induced cell death in pediatric acute lymphoblastic leukemia.Research resource: transcriptional response to glucocorticoids in childhood acute lymphoblastic leukemiamiR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer.Targeting the regulatory machinery of BIM for cancer therapy.Increased expression of microRNA-17 predicts poor prognosis in human glioma.Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway.MiR-17-5p and miR-20a promote chicken cell proliferation at least in part by upregulation of c-Myc via MAP3K2 targeting.The role of microRNAs in glucocorticoid action.Detection of microvesicle miRNA expression in ALL subtypes and analysis of their functional roles.
P2860
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P2860
Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@ast
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@en
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@nl
type
label
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@ast
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@en
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@nl
prefLabel
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@ast
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@en
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@nl
P2093
P2860
P356
P1476
Glucocorticoid-mediated repres ...... im and initiation of apoptosis
@en
P2093
Clark W Distelhorst
Jason K Molitoris
Karen S McColl
P2860
P304
P356
10.1210/ME.2010-0402
P577
2011-01-14T00:00:00Z