The T cell costimulator TL1A is induced by FcgammaR signaling in human monocytes and dendritic cells.
about
Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammationCytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBDThe TNF-family cytokine TL1A: from lymphocyte costimulator to disease co-conspiratorNew insights into the dichotomous role of innate cytokines in gut homeostasis and inflammationImmunopathology of inflammatory bowel diseaseOn death receptor 3 and its ligands…IBD-associated TL1A gene (TNFSF15) haplotypes determine increased expression of TL1A protein.TLR8-mediated activation of human monocytes inhibits TL1A expression.Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosisTumour necrosis factor superfamily members in the pathogenesis of inflammatory bowel diseaseAge-dependent maintenance of motor control and corticostriatal innervation by death receptor 3.Insights into IBD Pathogenesis.Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain sheddingA TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1.Use of animal models in elucidating disease pathogenesis in IBD.Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.The TNF-family cytokine TL1A inhibits proliferation of human activated B cellsProgranulin-derived Atsttrin directly binds to TNFRSF25 (DR3) and inhibits TNF-like ligand 1A (TL1A) activity.A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionalityCD161 DEFINES EFFECTOR T CELLS THAT EXPRESS LIGHT AND RESPOND TO TL1A-DR3 SIGNALING.Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL-22 production and IL-2-dependent proliferation.The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation.TNFSF15 Modulates Neovascularization and InflammationExpression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia.Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine ColitisTL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune diseaseSUSTAINED TL1A (TNFSF15) EXPRESSION ON BOTH LYMPHOID AND MYELOID CELLS LEADS TO MILD SPONTANEOUS INTESTINAL INFLAMMATION AND FIBROSIS.The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory ResponsesTL1A (TNFSF15) regulates the development of chronic colitis by modulating both T-helper 1 and T-helper 17 activation.A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection.A case-control study about the association between vascular endothelial growth inhibitor gene polymorphisms and breast cancer risk in female patients in Northeast China.Recent advances in IBD pathogenesis: genetics and immunobiology.The role of TNF superfamily members in T-cell function and diseases.Regulation and function of proinflammatory TH17 cells.The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseasesThe role of TL1A and DR3 in autoimmune and inflammatory diseases.TL1A and DR3, a TNF family ligand-receptor pair that promotes lymphocyte costimulation, mucosal hyperplasia, and autoimmune inflammation.Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells.T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria.Antibody-Fc receptor interactions in protection against intracellular pathogens.
P2860
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P2860
The T cell costimulator TL1A is induced by FcgammaR signaling in human monocytes and dendritic cells.
description
2007 nî lūn-bûn
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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
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2007年の論文
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
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name
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@ast
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@en
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@nl
type
label
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@ast
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@en
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@nl
prefLabel
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@ast
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@en
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@nl
P2093
P1476
The T cell costimulator TL1A i ...... monocytes and dendritic cells.
@en
P2093
Carol J Landers
John L Prehn
Kathrin S Michelsen
Lisa S Thomas
Stephan R Targan
P304
P356
10.4049/JIMMUNOL.178.7.4033
P407
P577
2007-04-01T00:00:00Z