Vascular patterning by Eph receptor tyrosine kinases and ephrins.
about
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signalingCrystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 ReceptorLigand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptorEphrin-B1 forward and reverse signaling are required during mouse developmentA mutant receptor tyrosine phosphatase, CD148, causes defects in vascular developmentPDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculatureRole of the 2 zebrafish survivin genes in vasculo-angiogenesis, neurogenesis, cardiogenesis and hematopoiesis.Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations.Trophoblasts, invasion, and microRNA.Discovery of tyrosine kinase inhibitors by docking into an inactive kinase conformation generated by molecular dynamics.Inhibition of tumor growth and angiogenesis by soluble EphB4.Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors.Unique structure and dynamics of the EphA5 ligand binding domain mediate its binding specificity as revealed by X-ray crystallography, NMR and MD simulationsMolecular control of arterial-venous blood vessel identity.New molecular pathways in angiogenesis.Eph receptors and ephrins as targets for cancer therapy.The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth.Translating angiogenesis research into the clinic: the challenges ahead.Identification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival.Gradients of Eph-A6 expression in primate retina suggest roles in both vascular and axon guidance.Ephrin expression and function in cancer.Targeting the DFG-in kinase conformation: a new trend emerging from a patent analysis.Glial influence on the blood brain barrier.EphB4 controls blood vascular morphogenesis during postnatal angiogenesis.Downregulation of EphA7 by hypermethylation in colorectal cancer.Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptorsEphrin-B2 expression critically influences Nipah virus infection independent of its cytoplasmic tail.DNA methylation in promoter region as biomarkers in prostate cancer.Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations.Beneficial role of pancreatic microenvironment for angiogenesis in transplanted pancreatic islets.Microvascular endowment in the developing chicken embryo lung.Overexpression of EphB4 in the mammary epithelium shifts the differentiation pathway of progenitor cells and promotes branching activity and vascularization.
P2860
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P2860
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@ast
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@en
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@nl
type
label
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@ast
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@en
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@nl
prefLabel
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@ast
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@en
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@nl
P356
P1476
Vascular patterning by Eph receptor tyrosine kinases and ephrins.
@en
P2093
Ralf H Adams
P356
10.1006/SCDB.2001.0289
P577
2002-02-01T00:00:00Z