Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence. - Wikidata - wikimedia - TriplyDB

Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.

Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.

http://www.wikidata.org/entity/Q34611139

about

Inflammatory and oxidative stress in rotavirus infection Viral Mimicry to Usurp Ubiquitin and SUMO Host Pathways Toll-like receptors in antiviral innate immunity Recent advances on viral manipulation of NF-κB signaling pathway Vaccinia virus protein A49 is an unexpected member of the B-cell Lymphoma (Bcl)-2 protein family EVM005: an ectromelia-encoded protein with dual roles in NF-κB inhibition and virulence SCFβ-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination.A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus.Putative E3 ubiquitin ligase of human rotavirus inhibits NF-κB activation by using molecular mimicry to target β-TrCP.Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling Microbial strategies for antagonizing Toll-like-receptor signal transduction.NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses.Enhancement of CD8(+) T-cell memory by removal of a vaccinia virus nuclear factor-κB inhibitor.Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins.Inhibition of Translation Initiation by Protein 169: A Vaccinia Virus Strategy to Suppress Innate and Adaptive Immunity and Alter Virus Virulence.The ORF61 Protein Encoded by Simian Varicella Virus and Varicella-Zoster Virus Inhibits NF-κB Signaling by Interfering with IκBα Degradation.Vaccinia Virus Protein C6 Inhibits Type I IFN Signalling in the Nucleus and Binds to the Transactivation Domain of STAT2 Vaccinia virus protein N2 is a nuclear IRF3 inhibitor that promotes virulence Rotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domain Multiple Bcl-2 family immunomodulators from vaccinia virus regulate MAPK/AP-1 activation Poxviral protein A52 stimulates p38 mitogen-activated protein kinase (MAPK) activation by causing tumor necrosis factor receptor-associated factor 6 (TRAF6) self-association leading to transforming growth factor β-activated kinase 1 (TAK1) recruitme Rotavirus NSP1 protein inhibits interferon-mediated STAT1 activation.Pathogens hijack the epigenome: a new twist on host-pathogen interactions.Vaccinia virus inhibits NF-κB-dependent gene expression downstream of p65 translocation.Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination.Advances in Antiviral Therapies Targeting Toll-like Receptors.Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infection Vaccinia virus virulence factor N1 can be ubiquitylated on multiple lysine residues.Rotavirus NSP1 Requires Casein Kinase II-Mediated Phosphorylation for Hijacking of Cullin-RING Ligases.A parapoxviral virion protein inhibits NF-κB signaling early in infection.Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis.Deletion of the K1L Gene Results in a Vaccinia Virus That Is Less Pathogenic Due to Muted Innate Immune Responses, yet Still Elicits Protective Immunity.Down the rabbit hole: Is necroptosis truly an innate response to infection?Distinct Roles of Vaccinia Virus NF-κB Inhibitor Proteins A52, B15, and K7 in the Immune Response.Molecular mimicry: good artists copy, great artists steal.Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP.A parapoxviral virion protein targets the retinoblastoma protein to inhibit NF-κB signaling.A comparison of the effect of molluscum contagiosum virus MC159 and MC160 proteins on vaccinia virus virulence in intranasal and intradermal infection routes.Virulent poxviruses inhibit DNA sensing by preventing STING activation.Suppression of NF-κB Activity: A Viral Immune Evasion Mechanism

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Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.

http://www.wikidata.org/entity/Q34611139

description

2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Poxvirus targeting of E3 ligas ...... immune evasion and virulence.

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Andrew G Bowie

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Brian J Ferguson

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Carlos Maluquer de Motes

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P2860

Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism

A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

Inhibition of IkappaB kinase by vaccinia virus virulence factor B14

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation

Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7

Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

Inhibition of Apoptosis and NF-κB Activation by Vaccinia Protein N1 Occur via Distinct Binding Surfaces and Make Different Contributions to Virulence

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