A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells.
about
Fluorescent proteins as genetically encoded FRET biosensors in life sciencesFluxes of lactate into, from, and among gap junction-coupled astrocytes and their interaction with noradrenalineIs L-lactate a novel signaling molecule in the brain?PII Protein-Derived FRET Sensors for Quantification and Live-Cell Imaging of 2-Oxoglutarate.Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activityEmergence of spatial structure in the tumor microenvironment due to the Warburg effectDroplet Microfluidic Platform for the Determination of Single-Cell Lactate Release.Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism.Nanomolar nitric oxide concentrations quickly and reversibly modulate astrocytic energy metabolismIn vivo biochemistry: applications for small molecule biosensors in plant biology.Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.NH4(+) triggers the release of astrocytic lactate via mitochondrial pyruvate shunting.High-resolution in vivo optical imaging of stroke injury and repair.Biofuel metabolic engineering with biosensors.Towards high resolution analysis of metabolic flux in cells and tissues.Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H+ secretion.Exploring cells with targeted biosensorsOpportunities for bioprocess monitoring using FRET biosensors.Concepts for regulation of axon integrity by enwrapping glia.Imaging and tracing of intracellular metabolites utilizing genetically encoded fluorescent biosensors.The metabolic response to excitotoxicity - lessons from single-cell imaging.Altered metabolic pathways in clear cell renal cell carcinoma: A meta-analysis and validation study focused on the deregulated genes and their associated networksIdentification and validation of dysregulated metabolic pathways in metastatic renal cell carcinoma.Single-cell imaging tools for brain energy metabolism: a review.FRET-based genetically-encoded sensors for quantitative monitoring of metabolites.In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD(+)/NADH redox state.Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity.Modulation of Mammary Stromal Cell Lactate Dynamics by Ambient Glucose and Epithelial Factors.Recent developments of genetically encoded optical sensors for cell biology.Genetically Encoded Fluorescent Biosensors to Explore AMPK Signaling and Energy Metabolism.Multifunctional role of astrocytes as gatekeepers of neuronal energy supplyConnexin-43 channels are a pathway for discharging lactate from glycolytic pancreatic ductal adenocarcinoma cells.Ratiometric Matryoshka biosensors from a nested cassette of green- and orange-emitting fluorescent proteinsSmall is fast: astrocytic glucose and lactate metabolism at cellular resolution.Imaging mitochondrial flux in single cells with a FRET sensor for pyruvate.Whole-cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production.Glutamine flux imaging using genetically encoded sensors.Imaging changes in the cytosolic ATP-to-ADP ratio.Functional interaction between bicarbonate transporters and carbonic anhydrase modulates lactate uptake into mouse cardiomyocytes.Current technical approaches to brain energy metabolism.
P2860
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P2860
A genetically encoded FRET lactate sensor and its use to detect the Warburg effect in single cancer cells.
description
2013 nî lūn-bûn
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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2013 թվականի փետրվարին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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A genetically encoded FRET lac ...... effect in single cancer cells.
@ast
A genetically encoded FRET lac ...... effect in single cancer cells.
@en
A genetically encoded FRET lac ...... effect in single cancer cells.
@nl
type
label
A genetically encoded FRET lac ...... effect in single cancer cells.
@ast
A genetically encoded FRET lac ...... effect in single cancer cells.
@en
A genetically encoded FRET lac ...... effect in single cancer cells.
@nl
prefLabel
A genetically encoded FRET lac ...... effect in single cancer cells.
@ast
A genetically encoded FRET lac ...... effect in single cancer cells.
@en
A genetically encoded FRET lac ...... effect in single cancer cells.
@nl
P2093
P2860
P1433
P1476
A genetically encoded FRET lac ...... effect in single cancer cells.
@en
P2093
Alejandro San Martín
Iván Ruminot
Luis Felipe Barros
Rodrigo Lerchundi
Sebastián Ceballo
P2860
P304
P356
10.1371/JOURNAL.PONE.0057712
P407
P577
2013-02-26T00:00:00Z