RIG-I- and MDA5-initiated innate immunity linked with adaptive immunity accelerates beta-cell death in fulminant type 1 diabetes - Wikidata - wikimedia - TriplyDB

RIG-I- and MDA5-initiated innate immunity linked with adaptive immunity accelerates beta-cell death in fulminant type 1 diabetes

RIG-I- and MDA5-initiated innate immunity linked with adaptive immunity accelerates beta-cell death in fulminant type 1 diabetes

http://www.wikidata.org/entity/Q34615467

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Dendritic cell subsets in type 1 diabetes: friend or foe?Distinct cell clusters touching islet cells induce islet cell replication in association with over-expression of Regenerating Gene (REG) protein in fulminant type 1 diabetes MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA Increased expression of IL-18 in the serum and islets of type 1 diabetics.Viral infection of engrafted human islets leads to diabetes.Antibody-validated proteins in inflamed islets of fulminant type 1 diabetes profiled by laser-capture microdissection followed by mass spectrometry.Expression and regulation of chemokines in murine and human type 1 diabetes.Etiopathogenesis of insulin autoimmunity.The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes.RIG-I inhibits pancreatic β cell proliferation through competitive binding of activated Src.Ancient origins of vertebrate-specific innate antiviral immunity.Enter at your own risk: how enteroviruses navigate the dangerous world of pattern recognition receptor signaling.Recent Findings on Fulminant Type 1 Diabetes.Innate Viral Receptor Signaling Determines Type 1 Diabetes Onset.Fulminant Type 1 Diabetes in Children: A Multicenter Study in China.Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins.Pathological changes in the pancreas of fulminant type 1 diabetes and slowly progressive insulin-dependent diabetes mellitus (SPIDDM): innate immunity in fulminant type 1 diabetes and SPIDDM.Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry?Insulin-producing cells derived from 'induced pluripotent stem cells' of patients with fulminant type 1 diabetes: Vulnerability to cytokine insults and increased expression of apoptosis-related genes.Distinct Inflammatory Changes of the Pancreas of Slowly Progressive Insulin-dependent (Type 1) Diabetes

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RIG-I- and MDA5-initiated innate immunity linked with adaptive immunity accelerates beta-cell death in fulminant type 1 diabetes

http://www.wikidata.org/entity/Q34615467

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

RIG-I- and MDA5-initiated inna ...... h in fulminant type 1 diabetes

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RIG-I- and MDA5-initiated inna ...... h in fulminant type 1 diabetes

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RIG-I- and MDA5-initiated inna ...... h in fulminant type 1 diabetes

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Akio Kawaguchi

http://www.w3.org/2001/XMLSchema#string

Akira Shimada

http://www.w3.org/2001/XMLSchema#string

Daiichiro Akiyama

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Fumihiko Furuya

http://www.w3.org/2001/XMLSchema#string

Hideki Fujii

http://www.w3.org/2001/XMLSchema#string

Hiroki Shimura

http://www.w3.org/2001/XMLSchema#string

Jun Itakura

http://www.w3.org/2001/XMLSchema#string

Kaoru Aida

http://www.w3.org/2001/XMLSchema#string

Masahiro Kaneshige

http://www.w3.org/2001/XMLSchema#string

Masako Suzuki

http://www.w3.org/2001/XMLSchema#string

P2860

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

A novel tumor suppressor protein promotes keratinocyte terminal differentiation via activation of type I transglutaminase

Cloning of a new cytokine that induces IFN-gamma production by T cells

Apoptosis by death factor

IRF-7 is the master regulator of type-I interferon-dependent immune responses

Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells.

IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells.

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.

MDA5/RIG-I and virus recognition.

Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells

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884-889

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scholarly article

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10.2337/DB10-0795

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3

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60

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49805846

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21289206

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type-1 diabetes

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3046849

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