Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.
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T-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevanceUpdate on Advances in Research on Idiosyncratic Drug-Induced Liver InjuryNew genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivityIdiosyncratic adverse drug reactions: current conceptsDrug allergy: causes and desensitizationSynergistic effect between amoxicillin and TLR ligands on dendritic cells from amoxicillin-delayed allergic patientsHepatic expression profiles in retroviral infection: relevance to drug hypersensitivity risk.Cytochrome b5 and NADH cytochrome b5 reductase: genotype-phenotype correlations for hydroxylamine reduction.Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine.Drug antigenicity, immunogenicity, and costimulatory signaling: evidence for formation of a functional antigen through immune cell metabolism.Hypersensitivity reactions to HIV therapy.Delayed drug hypersensitivity: models of T-cell stimulationTreatment of DIHS/DRESS syndrome with combined N-acetylcysteine, prednisone and valganciclovir--a hypothesisTherapeutic options for Stenotrophomonas maltophilia infections beyond co-trimoxazole: a systematic review."Danger" conditions increase sulfamethoxazole-protein adduct formation in human antigen-presenting cellsImmune mediation of hypersensitivity adverse drug reactions: implications for therapy.Animal models of toxic epidermal necrolysis.Managing the challenge of chemically reactive metabolites in drug development.Human leukocyte antigens (HLA) associated drug hypersensitivity: consequences of drug binding to HLA.The generation, detection, and effects of reactive drug metabolites.Hepatotoxicity: a scheme for generating chemical categories for read-across, structural alerts and insights into mechanism(s) of action.Bioactivation of drugs in the skin: relationship to cutaneous adverse drug reactions.In vitro testing for diagnosis of idiosyncratic adverse drug reactions: Implications for pathophysiology.Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions?Allopurinol induces innate immune responses through mitogen-activated protein kinase signaling pathways in HL-60 cells.Canine progenitor epidermal keratinocytes express various inflammatory markers, including interleukin-8 and CD40, which are affected by certain antibiotics.Systemic drugs inducing non-immediate cutaneous adverse reactions and contact sensitizers evoke similar responses in THP-1 cells.In silico Prediction of Drug Induced Liver Toxicity Using Substructure Pattern Recognition Method.Chemical or drug hypersensitivity: is the immune system clearing the danger?The p-i Concept: Pharmacological Interaction of Drugs With Immune Receptors.Functional changes of dendritic cells in hypersensivity reactions to amoxicillin.Ammonium perfluorooctanoate substantially alters phenotype and cytokine secretion of human monocyte-derived dendritic cells in vitro.Expression of N-acetyltransferase in monocyte-derived dendritic cells.TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole.The predictive value of the in vitro platelet toxicity assay (iPTA) for the diagnosis of hypersensitivity reactions to sulfonamides.Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells.From the Cover: Characterization of Isoniazid-Specific T-Cell Clones in Patients with anti-Tuberculosis Drug-Related Liver and Skin Injury.HLA-DQ allele-restricted activation of nitroso sulfamethoxazole-specific CD4-positive T lymphocytes from patients with cystic fibrosis.RNA expression profiling in sulfamethoxazole-treated patients with a range of in vitro lymphocyte cytotoxicity phenotypes.HIV-1 tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells.
P2860
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P2860
Sulfamethoxazole and its metabolite nitroso sulfamethoxazole stimulate dendritic cell costimulatory signaling.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@ast
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@en
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@nl
type
label
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@ast
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@en
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@nl
prefLabel
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@ast
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@en
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@nl
P2093
P1476
Sulfamethoxazole and its metab ...... cell costimulatory signaling.
@en
P2093
B Kevin Park
Charlotte A Ashby
Dean J Naisbitt
Joseph P Sanderson
M Jane Tucker
Michael J Rieder
Stephen E Clarke
P304
P356
10.4049/JIMMUNOL.178.9.5533
P407
P577
2007-05-01T00:00:00Z