Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans
about
ehavioral GeneticsGenotype-environment interactions for quantitative traits in Korea Associated Resource (KARE) cohorts.Practical considerations regarding the use of genotype and pedigree data to model relatedness in the context of genome-wide association studiesUsing genomics to characterize evolutionary potential for conservation of wild populationsIntegration of summary data from GWAS and eQTL studies predicts complex trait gene targets.Estimation and partition of heritability in human populations using whole-genome analysis methods.Estimating the heritability of colorectal cancer.Large-scale genomics unveils the genetic architecture of psychiatric disordersGlobal genetic variations predict brain response to faces.Substantial SNP-based heritability estimates for working memory performanceQuantifying missing heritability at known GWAS loci.Population genetic differentiation of height and body mass index across Europe.Genotype-environment correlation in the era of DNAAge- and gender-dependent heterogeneous proportion of variation explained by SNPs in quantitative traits reflecting human healthFrom SNP co-association to RNA co-expression: novel insights into gene networks for intramuscular fatty acid composition in porcineA multi-trait, meta-analysis for detecting pleiotropic polymorphisms for stature, fatness and reproduction in beef cattle.Dominance genetic variation contributes little to the missing heritability for human complex traits.The obesity-risk variant of FTO is inversely related with the So-Eum constitutional type: genome-wide association and replication analysesGenome-wide association study dissects genetic architecture underlying longitudinal egg weights in chickens.Genetic associations and shared environmental effects on the skin microbiome of Korean twins.Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.Explaining additional genetic variation in complex traitsHeritability Estimated Using 50K SNPs Indicates Missing Heritability Problem in Holstein Breeding.Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairs.Concepts, estimation and interpretation of SNP-based heritability.10 Years of GWAS Discovery: Biology, Function, and Translation.Genotypic Context and Epistasis in Individuals and Populations.The Genetic Architecture of Gene Expression in Peripheral Blood.MicroRNAs enrichment in GWAS of complex human phenotypes.Pharmacogenomic variants have larger effect sizes than genetic variants associated with other dichotomous complex traits.Effect of allele frequencies, effect sizes and number of markers on prediction of quantitative traits in chickens.Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits.Global genetic differentiation of complex traits shaped by natural selection in humans.
P2860
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P2860
Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@ast
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@en
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@nl
type
label
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@ast
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@en
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@nl
prefLabel
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@ast
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@en
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@nl
P2093
P2860
P1433
P1476
Ubiquitous polygenicity of hum ...... alysis of 49 traits in Koreans
@en
P2093
Bok-Ghee Han
Hyun-Jeong Lee
Jaemin Kim
Jong-Young Lee
Myeong-Chan Cho
Taeheon Lee
P2860
P304
P356
10.1371/JOURNAL.PGEN.1003355
P577
2013-03-07T00:00:00Z