Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.
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Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architectureUncovering the Genetic Architectures of Quantitative TraitsThe impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular diseasePharmacogenomics in diabetes mellitus: insights into drug action and drug discoveryMeta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across StudiesRare and low-frequency coding variants alter human adult heightExposing the exposures responsible for type 2 diabetes and obesity.Epidemiology of cardiovascular disease: recent novel outlooks on risk factors and clinical approaches.Phenome-wide heritability analysis of the UK Biobank1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.Quantifying the mapping precision of genome-wide association studies using whole-genome sequencing dataIdentification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis.An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association StudiesSmokescreen: a targeted genotyping array for addiction researchTransethnic Genetic-Correlation Estimates from Summary Statistics.Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traitsFunctional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression.A Model of Compound Heterozygous, Loss-of-Function Alleles Is Broadly Consistent with Observations from Complex-Disease GWAS Datasets.Estimating Modifying Effect of Age on Genetic and Environmental Variance Components in Twin ModelsMitonuclear Epistasis for Development Time and Its Modification by Diet in Drosophila.Assessing the genetic overlap between BMI and cognitive functionAccuracy of heritability estimations in presence of hidden population stratification.The case for genome-wide association studies of bone acquisition in paediatric and adolescent populationsAdult height, nutrition, and population health.Fast and Accurate Construction of Confidence Intervals for Heritability.Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts.Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants.Ultra-rare disruptive and damaging mutations influence educational attainment in the general population.Autosomal genetic control of human gene expression does not differ across the sexes.Concepts, estimation and interpretation of SNP-based heritability.Embracing polygenicity: a review of methods and tools for psychiatric genetics research.Detection and quantification of inbreeding depression for complex traits from SNP data.Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits.10 Years of GWAS Discovery: Biology, Function, and Translation.Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Reevaluation of SNP heritability in complex human traits.The Genetic Architecture of Major Depressive Disorder in Han Chinese Women.Population-based approaches to genetics of migraine.Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes
P2860
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P2860
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Genetic variance estimation wi ...... an height and body mass index.
@ast
Genetic variance estimation wi ...... an height and body mass index.
@en
type
label
Genetic variance estimation wi ...... an height and body mass index.
@ast
Genetic variance estimation wi ...... an height and body mass index.
@en
prefLabel
Genetic variance estimation wi ...... an height and body mass index.
@ast
Genetic variance estimation wi ...... an height and body mass index.
@en
P2093
P2860
P50
P356
P1433
P1476
Genetic variance estimation wi ...... an height and body mass index.
@en
P2093
Anna A E Vinkhuyzen
Harold Snieder
Ilja M Nolte
John R B Perry
LifeLines Cohort Study
Matthew C Keller
Nancy L Pedersen
Naomi R Wray
P2860
P2888
P304
P356
10.1038/NG.3390
P407
P50
P577
2015-08-31T00:00:00Z