The 5' terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner.
about
Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translationAbnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemiaRegulation of global and specific mRNA translation by the mTOR signaling pathwayThe expanding role of mTOR in cancer cell growth and proliferationWhat Is the Impact of mRNA 5' TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?A maize insulin-like growth factor signals to a transduction pathway that regulates protein synthesis in maizeRapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug.Path to facilitate the prediction of functional amino acid substitutions in red blood cell disorders--a computational approachS6 phosphorylation-independent pathways regulate translation of 5'-terminal oligopyrimidine tract-containing mRNAs in differentiating hematopoietic cells.CART classification of human 5' UTR sequencesUnified translation repression mechanism for microRNAs and upstream AUGsThe role of c-myc in cellular growth control.Targeting the translational machinery as a novel treatment strategy for hematologic malignanciesA highly recurrent RPS27 5'UTR mutation in melanoma.Translational control of viral gene expression in eukaryotesThe binding of TIA-1 to RNA C-rich sequences is driven by its C-terminal RRM domain.Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylationExtensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformationCellular differences in protein synthesis regulate tissue homeostasis.The expression of poly(A)-binding protein gene is translationally regulated in a growth-dependent fashion through a 5'-terminal oligopyrimidine tract motif.The relationship between mTOR signalling pathway and recombinant antibody productivity in CHO cell lines.Functional role of RNA polymerase II and P70 S6 kinase in KCl withdrawal-induced cerebellar granule neuron apoptosis.Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs.Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome.Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR.Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract.Virus-induced translational arrest through 4EBP1/2-dependent decay of 5'-TOP mRNAs restricts viral infection.Identification of mRNAs that continue to associate with polysomes during hypoxia.Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.An Inhibitory Motif on the 5'UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies.Translational research? Ribosome integrity and a new p53 tumor suppressor checkpoint.In silico motif analysis suggests an interplay of transcriptional and translational control in mTOR responseOncogenic AKTivation of translation as a therapeutic target.Comprehensive analysis of nucleocytoplasmic dynamics of mRNA in Drosophila cells.Stress puts TIA on TOP.Lithium can relieve translational repression of TOP mRNAs elicited by various blocks along the cell cycle in a glycogen synthase kinase-3- and S6-kinase-independent manner.Translation of both 5'TOP and non-TOP host mRNAs continues into the late phase of Baculovirus infection.All translation elongation factors and the e, f, and h subunits of translation initiation factor 3 are encoded by 5'-terminal oligopyrimidine (TOP) mRNAsBroad role for YBX1 in defining the small noncoding RNA composition of exosomes.Overexpression of poly(A)-binding protein down-regulates the translation or the abundance of its own mRNA.
P2860
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P2860
The 5' terminal oligopyrimidine tract confers translational control on TOP mRNAs in a cell type- and sequence context-dependent manner.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@ast
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@en
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@nl
type
label
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@ast
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@en
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@nl
prefLabel
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@ast
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@en
The 5' terminal oligopyrimidin ...... ence context-dependent manner.
@nl
P2860
P356
P1476
The 5' terminal oligopyrimidin ...... uence context-dependent manner
@en
P2093
P2860
P304
P356
10.1093/NAR/25.5.995
P407
P50
P577
1997-03-01T00:00:00Z