6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1

6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1

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http://www.wikidata.org/entity/Q34629933
The role of aberrant proteolysis in lymphomagenesisComprehensive characterization of (S)GTP-binding proteins by orthogonal quantitative (S)GTP-affinity profiling and (S)GTP/GTP competition assays.6-Thioguanine and zebularine down-regulate DNMT1 and globally demethylate canine malignant lymphoid cells.Fludarabine downregulates indoleamine 2,3-dioxygenase in tumors via a proteasome-mediated degradation mechanism.Cyclophosphamide perturbs cytosine methylation in Jurkat-T cells through LSD1-mediated stabilization of DNMT1 protein.Microbiome-Epigenome Interactions and the Environmental Origins of Inflammatory Bowel DiseasesEffects of 6-thioguanine and S6-methylthioguanine on transcription in vitro and in human cells.Tissue banking, bioinformatics, and electronic medical records: the front-end requirements for personalized medicine.Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.DNA-intercalators causing rapid re-expression of methylated and silenced genes in cancer cellsTargeting Histone Demethylases: A New Avenue for the Fight against Cancer.LSD1 inhibitors: a patent review (2010-2015).Challenges for epigenetic research in inflammatory bowel diseases.Novel Insights into the Molecular Mechanism of Action of DNA Hypomethylating Agents: Role of Protein Kinase C δ in Decitabine-Induced Degradation of DNA Methyltransferase 1.The impact of 6-thioguanine incorporation into DNA on the function of DNA methyltransferase Dnmt3a.
P2860

6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1

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http://www.wikidata.org/entity/Q34629933
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@ast
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@en
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@nl
type
label
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@ast
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@en
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@nl
prefLabel
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@ast
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@en
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
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P50
P577
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P921
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P1433
P1476
6-Thioguanine reactivates epig ...... -mediated degradation of DNMT1
@en
P2093
P2860
P304
P31
P356
10.1158/0008-5472.CAN-10-3430
P407
P433
P478
P50
P577
P698
P921
P932