about
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural featuresIdentification of JL1037 as a novel, specific, reversible lysine-specific demethylase 1 inhibitor that induce apoptosis and autophagy of AML cellsAdvances toward LSD1 inhibitors for cancer therapy.Toward development of epigenetic drugs for central nervous system disorders: Modulating neuroplasticity via H3K4 methylation.Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer.Stress-induced phosphoprotein 1 acts as a scaffold protein for glycogen synthase kinase-3 beta-mediated phosphorylation of lysine-specific demethylase 1.KDM1A microenvironment, its oncogenic potential, and therapeutic significance.Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations
P2860
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P2860
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
LSD1 inhibitors: a patent review (2010-2015).
@en
type
label
LSD1 inhibitors: a patent review (2010-2015).
@en
prefLabel
LSD1 inhibitors: a patent review (2010-2015).
@en
P2860
P50
P1476
LSD1 inhibitors: a patent review (2010-2015).
@en
P2860
P304
P356
10.1517/13543776.2016.1165209
P407
P577
2016-03-28T00:00:00Z