Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association. - Wikidata - wikimedia - TriplyDB

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

http://www.wikidata.org/entity/Q34635511

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The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers Next generation sequencing of acute myeloid leukemia: influencing prognosis.Clinical impact of gene mutations and lesions detected by SNP-array karyotyping in acute myeloid leukemia patients in the context of gemtuzumab ozogamicin treatment: results of the ALFA-0701 trial.MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin.Clinical features of de novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations.Mutation patterns of 16 genes in primary and secondary acute myeloid leukemia (AML) with normal cytogenetics.DNMT3A in haematological malignancies.High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia.DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies DNMT3A Mutational Status Affects the Results of Dose-Escalated Induction Therapy in Acute Myelogenous Leukemia Incidence and prognostic impact of DNMT3A mutations in Korean normal karyotype acute myeloid leukemia patients.Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia Association between DNMT3A mutations and prognosis of adults with de novo acute myeloid leukemia: a systematic review and meta-analysis Epigenetics in diagnosis, prognostic assessment and treatment of cancer: an update.DNMT3A R882 Mutations Predict a Poor Prognosis in AML: A Meta-Analysis From 4474 Patients DNMT3A Mutations in Patients with Acute Myeloid Leukemia in South Brazil.DNA methyltransferase 3a rs1550117 genetic polymorphism predicts poor survival in gastric cancer patients.IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association.Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.Acute myeloid leukemia with translocation t(3;5): new molecular insights.Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia.Evaluation of DNMT3A genetic polymorphisms as outcome predictors in AML patients.Mutation profiling of 19 candidate genes in acute myeloid leukemia suggests significance of DNMT3A mutations Molecular markers in acute myeloid leukaemia.Genomic tools in acute myeloid leukemia: From the bench to the bedside Prognostic factors for acute myeloid leukaemia in adults--biological significance and clinical use.Allogeneic hematopoietic cell transplantation for acute myeloid leukemia during first complete remission: a clinical perspective.Targeted therapy of acute myeloid leukemia.Epigenetic modifiers in normal and malignant hematopoiesis.Acute Myeloid Leukemia With Recurrent Genetic Abnormalities Other Than Translocations.Driver mutations of cancer epigenomes.Mutations in epigenetic modifiers in acute myeloid leukemia and their clinical utility.DNA methylation in normal and malignant hematopoiesis.Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines.DNMT3A in Leukemia.Biological and clinical consequences of NPM1 mutations in AML.Copy-number analysis identified new prognostic marker in acute myeloid leukemia.Epimutations mimic genomic mutations of DNMT3A in acute myeloid leukemia.Allogeneic hematopoietic stem cell transplantation could improve survival of cytogenetically normal adult acute myeloid leukemia patients with DNMT3A mutations.DNMT3A mutations in Chinese childhood acute myeloid leukemia.

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Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

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Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Recurring mutations found by sequencing an acute myeloid leukemia genome

DNMT3A Mutations in Acute Myeloid Leukemia

Prevalence, clinical profile, and prognosis of NPM mutations in AML with normal karyotype.

Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations.

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype.

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Wilms tumor 1 gene mutations are associated with a higher risk of recurrence in young adults with acute myeloid leukemia: a study from the Acute Leukemia French Association.

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

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