Pathophysiology of inhibitors to factor VIII in patients with haemophilia A. - Wikidata - wikimedia - TriplyDB

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

http://www.wikidata.org/entity/Q34636981

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Regulatory T cell epitopes (Tregitopes) in IgG induce tolerance in vivo and lack immunogenicity per se.Effect of HLA DR epitope de-immunization of Factor VIII in vitro and in vivo.Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.Canadian multi-institutional survey of immune tolerance therapy (ITT) -- experience with the use of recombinant factor VIII for ITT.Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A.Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A.Identification and removal of a promiscuous CD4+ T cell epitope from the C1 domain of factor VIII.Catastrophic microangiopathy induced by high-titre factor VIII inhibitors after liver transplantation for haemophilia A with cirrhosis.Population-specific design of de-immunized protein biotherapeutics.

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Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

http://www.wikidata.org/entity/Q34636981

description

2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002 թվականի մայիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

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Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

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Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

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type

label

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

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Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

@en

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

@nl

prefLabel

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

@ast

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

@en

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A.

@nl

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J.1365-2516.2002.00624.X

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P1476

Pathophysiology of inhibitors to factor VIII in patients with haemophilia A

@en

P2093

B Drayton

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C Artaud

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M D Kazatchkine

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N Misra

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S V Kaveri

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P2860

Structure of the C2 domain of human factor VIII at 1.5 A resolution

Multiple VH genes are used to assemble human antibodies directed toward the A3-C1 domains of factor VIII.

Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.

Inhibition of human factor VIIIa by anti-A2 subunit antibodies.

Healthy subjects produce both anti-factor VIII and specific anti-idiotypic antibodies.

The immunologic character of acquired inhibitors of antihemophilic globulin (factor 8) and the kinetics of their interaction with factor 8.

Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII

Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.

Recovery from anti-VIII:C (antihemophilic factor) autoimmune disease is dependent on generation of antiidiotypes against anti-VIII:C autoantibodies.

Long-term expression of human coagulation factor VIII and correction of hemophilia A after in vivo retroviral gene transfer in factor VIII-deficient mice.

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273-279

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scholarly article

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10.1046/J.1365-2516.2002.00624.X

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3

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8

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Jagadeesh Bayry

Sébastien Lacroix-Desmazes

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2002-05-01T00:00:00Z

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12010423

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pathophysiology

Coagulation factor VIII