The significance of vascular and neural apoptosis to the pathology of diabetic retinopathy. - Wikidata - wikimedia - TriplyDB

The significance of vascular and neural apoptosis to the pathology of diabetic retinopathy.

The significance of vascular and neural apoptosis to the pathology of diabetic retinopathy.

http://www.wikidata.org/entity/Q34645612

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Ocular Complications of Diabetes and Therapeutic Approaches Brain and Retinal Pericytes: Origin, Function and Role Pathophysiology of diabetic retinopathy Primary retinal cultures as a tool for modeling diabetic retinopathy: an overview Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy Mitochondrial function in vascular endothelial cell in diabetes High glucose-induced downregulation of connexin 30.2 promotes retinal vascular lesions: implications for diabetic retinopathy Cone Photoreceptor Irregularity on Adaptive Optics Scanning Laser Ophthalmoscopy Correlates With Severity of Diabetic Retinopathy and Macular Edema.Conditional Müllercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model.The db/db mouse: a useful model for the study of diabetic retinal neurodegeneration.A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy.Loss of synaptic connectivity, particularly in second order neurons is a key feature of diabetic retinal neuropathy in the Ins2Akita mouse.Plastic roles of pericytes in the blood-retinal barrier.Correlation of retinal nerve fibre layer and macular thickness with serum uric acid among type 2 diabetes mellitus Protective and antioxidant effects of PPARα in the ischemic retina.High glucose decreases expression and activity of p-glycoprotein in cultured human retinal pigment epithelium possibly through iNOS induction.Peroxisome proliferator-activated receptor α protects capillary pericytes in the retina.Exendin-4 protects retinal cells from early diabetes in Goto-Kakizaki rats by increasing the Bcl-2/Bax and Bcl-xL/Bax ratios and reducing reactive gliosis.Influence of retinopathy on the achromatic and chromatic vision of patients with type 2 diabetes Protective effects of astragaloside IV on db/db mice with diabetic retinopathy Absence of clinical correlates of diabetic retinopathy in the Ins2Akita retina.Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis.Arginase in retinopathy.The effects of pleiotrophin in proliferative diabetic retinopathy Diabetes and retinal vascular dysfunction.Neonatal hyperglycemia inhibits angiogenesis and induces inflammation and neuronal degeneration in the retina α-Melanocyte-stimulating hormone protects retinal vascular endothelial cells from oxidative stress and apoptosis in a rat model of diabetes Retinal Neurodegeneration in db/db Mice at the Early Period of Diabetes.Environmental enrichment protects the retina from early diabetic damage in adult rats.Systemic administration of erythropoietin inhibits retinopathy in RCS rats.High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes Color vision and neuroretinal function in diabetes.Enriched Environment Protects the Optic Nerve from Early Diabetes-Induced Damage in Adult Rats.TXNIP links innate host defense mechanisms to oxidative stress and inflammation in retinal Muller glia under chronic hyperglycemia: implications for diabetic retinopathy.Diabetic levels of glucose increase cellular reducing equivalents but reduce survival in three models of 661W photoreceptor-like cell injury Reversal of the Caspase-Dependent Apoptotic Cytotoxicity Pathway by Taurine from Lycium barbarum (Goji Berry) in Human Retinal Pigment Epithelial Cells: Potential Benefit in Diabetic Retinopathy.Early neurodegeneration in the retina of type 2 diabetic patients.The Multifocal On- and Off-Responses in the Human Diabetic Retina.Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease

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The significance of vascular and neural apoptosis to the pathology of diabetic retinopathy.

http://www.wikidata.org/entity/Q34645612

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2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2011年の論文

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Investigative Ophthalmology & Visual Science

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Alistair J Barber

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Steven F Abcouwer

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Thomas W Gardner

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P2860

Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro

Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity

Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy

Elevated glucose changes the expression of ionotropic glutamate receptor subunits and impairs calcium homeostasis in retinal neural cells

Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Mapping retinal fluorescein leakage with confocal scanning laser fluorometry of the human vitreous.

Retinal nerve fibre layer loss in patients with type 1 diabetes mellitus without retinopathy.

Characterization of microglial cells and their response to stimulation in an organotypic retinal culture system.

Retinal glutamate in diabetes and effect of antioxidants.

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