The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes
about
Oncogenic homeodomain transcription factor E2A-Pbx1 activates a novel WNT gene in pre-B acute lymphoblastoid leukemiaStructural studies of a stable parallel-stranded DNA duplex incorporating isoguanine:cytosine and isocytosine:guanine basepairs by nuclear magnetic resonance spectroscopySmall interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.Predicting oligonucleotide affinity to nucleic acid targets.Improved targeting of miRNA with antisense oligonucleotidesNanomaterials based on DNACrystallographic studies of chemically modified nucleic acids: a backward glanceRestoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patientsChimeric RNase H-competent oligonucleotides directed to the HIV-1 Rev response elementThe influence of locked nucleic acid residues on the thermodynamic properties of 2'-O-methyl RNA/RNA heteroduplexesSyntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine.Synthesis and hybridization studies of oligonucleotides containing 1-(2-deoxy-2-alpha-C-hydroxymethyl-beta-D-ribofuranosyl)thymine (2'-alpha-hm-dT).Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid GuidesStructural origins of the exonuclease resistance of a zwitterionic RNASolution structure of a DNA duplex with a chiral alkyl phosphonate moietyCrystal structures of DNA:DNA and DNA:RNA duplexes containing 5-(N-aminohexyl)carbamoyl-modified uracils reveal the basis for properties as antigene and antisense moleculesNucleation, propagation and cleavage of target RNAs in Ago silencing complexes.Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Nonionic Modifications Better than DNADifferential stability of 2'F-ANA*RNA and ANA*RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibilityAn Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNAStructure and nuclease resistance of 2′,4′-constrained 2′-O-methoxyethyl (cMOE) and 2′-O-ethyl (cEt) modified DNAsAmides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAsStructural insight into DNA-assembled oligochromophores: crystallographic analysis of pyrene- and phenanthrene-modified DNA in complex with BpuJI endonucleaseCrystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stabilityThermodynamics of 2'-ribose substitutions in UUCG tetraloops227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?Winnowing DNA for rare sequences: highly specific sequence and methylation based enrichmentHsp90 protein interacts with phosphorothioate oligonucleotides containing hydrophobic 2'-modifications and enhances antisense activitySilencing disease genes in the laboratory and the clinicRecognition of DNA by strand invasion with oligonucleotide-spermine conjugates.Oligonucleotide-peptide conjugates as potential antisense agents.Nucleic Acid Nanostructures: Bottom-Up Control of Geometry on the NanoscaleDesign and applications of modified oligonucleotides.Synthesis and monitored selection of 5'-nucleobase-capped oligodeoxyribonucleotides.Oligonucleotide-based knockdown technologies: antisense versus RNA interference.A novel concept for ligand attachment to oligonucleotides via a 2'-succinyl linker.Applications of mass spectrometry to the study of siRNA.Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data.Optimized synthesis of phosphorothioate oligodeoxyribonucleotides substituted with a 5'-protected thiol function and a 3'-amino group.Making drugs out of oligonucleotides: a brief review and perspective.
P2860
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P2860
The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes
description
1997 nî lūn-bûn
@nan
1997 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@ast
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@en
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@nl
type
label
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@ast
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@en
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@nl
prefLabel
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@ast
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@en
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@nl
P2860
P356
P1476
The ups and downs of nucleic a ...... ally-modified DNA:RNA duplexes
@en
P2093
P2860
P304
P356
10.1093/NAR/25.22.4429
P407
P577
1997-11-01T00:00:00Z