Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
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Transcriptional regulation of chemokine genes: a link to pancreatic islet inflammation?Insulitis in human type 1 diabetes: a comparison between patients and animal modelsA type I interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes.The central role of antigen presentation in islets of Langerhans in autoimmune diabetesZnT8-reactive T cells are weakly pathogenic in NOD mice but can participate in diabetes under inflammatory conditionsA minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes.Inhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.Population dynamics of islet-infiltrating cells in autoimmune diabetes.Induction of indoleamine 2, 3-dioxygenase in human dendritic cells by a cholera toxin B subunit-proinsulin vaccine.Use of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetesThe Role of Dendritic Cell Subsets and Innate Immunity in the Pathogenesis of Type 1 Diabetes and Other Autoimmune Diseases.E2-2 Dependent Plasmacytoid Dendritic Cells Control Autoimmune Diabetes.Heterogeneity and Lobularity of Pancreatic Pathology in Type 1 Diabetes during the Prediabetic PhaseRapid, high efficiency isolation of pancreatic ß-cells.Thioreductase-Containing Epitopes Inhibit the Development of Type 1 Diabetes in the NOD Mouse Model.Antigen presentation events during the initiation of autoimmune diabetes in the NOD mouseB-lymphocytes expressing an immunoglobulin specificity recognizing the pancreatic ß-cell autoantigen peripherin are potent contributors to type 1 diabetes development in NOD mice.The role of islet antigen presenting cells and the presentation of insulin in the initiation of autoimmune diabetes in the NOD mouse.Pathogenic CD4⁺ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes.Anti-coreceptor therapy drives selective T cell egress by suppressing inflammation-dependent chemotactic cues.Autoimmune manifestations in aged mice arise from early-life immune dysregulation.Antigen-specific therapy against type 1 diabetes: mechanisms and perspectives.Pancreatic pathology in type 1 diabetes mellitus.The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro.Involvement of long non-coding RNAs in beta cell failure at the onset of type 1 diabetes in NOD mice.Macrophages and dendritic cells in islets of Langerhans in diabetic autoimmunity: a lesson on cell interactions in a mini-organ.Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis.The Importance of Dendritic Cells in Maintaining Immune Tolerance.Understanding type 1 diabetes through proteomics.Type 1 Diabetes and Type 1 Interferonopathies: Localization of a Type 1 Common Thread of Virus Infection in the Pancreas.The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation.Type I Interferon Is a Catastrophic Feature of the Diabetic Islet MicroenvironmentAIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating AutoantibodiesProgression of type 1 diabetes from the prediabetic stage is controlled by interferon-α signalingHyaluronan content governs tissue stiffness in pancreatic islet inflammation.Cutting Edge: Origins, Recruitment, and Regulation of CD11c+ Cells in Inflamed Islets of Autoimmune Diabetes Mice.Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice.Type 1 Interferons Potentiate Human CD8+ T-Cell Cytotoxicity Through a STAT4- and Granzyme B-Dependent Pathway.The islet-resident macrophage is in an inflammatory state and senses microbial products in blood.Shuffling peptides to create T-cell epitopes: does the immune system play cards?
P2860
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P2860
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
description
2013 nî lūn-bûn
@nan
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@ast
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@en
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@nl
type
label
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@ast
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@en
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@nl
prefLabel
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@ast
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@en
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@nl
P2093
P2860
P1433
P1476
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
@en
P2093
Fadi Towfic
Javier A Carrero
Maxim N Artyomov
P2860
P304
P356
10.1371/JOURNAL.PONE.0059701
P407
P577
2013-03-26T00:00:00Z